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盆炎丸治疗解脲脲原体感染气虚血瘀证患者的临床观察

[Treatment of ureaplasma urealyticum infection patients of Qi deficiency blood stasis syndrome by pengyan pill: a clinical observation].

作者信息

Liu Wen-E, Tan Zhen-Yu, Xia Ru-Yi, Zou Zhi-Xiang, Gao Wei-Hui, Kuang Ji-Lin, Ding Liang-lian

机构信息

Department of Obstetrics and Gynecology, First Affiliated Hospital, Hunan University of Traditional Chinese Medicine, Changsha 410007, China.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 May;33(5):590-3.

Abstract

OBJECTIVE

To observe the clinical efficacy of penyan pill (PP) in treating ureaplasma urealyticum (UU) infection patients of qi deficiency blood stasis syndrome (QDBSS).

METHODS

Totally 188 UU infection patients of QDBSS were randomly assigned to two groups, the treatment group and the control group. Patients in the treatment group were treated with PP (10 g each time, thrice daily, 14 consecutive days as one therapeutic course), while those in the control group took azithromycin (10 g each day, 7 consecutive days as one therapeutic course). They were continually treated for 3 therapeutic courses. The clinical symptom integrals were observed in the two groups before and after treatment. The short-term efficacy was judged. Their recurrence rates were followed-up to assess their long-term efficacies.

RESULTS

The total effective rate of the comprehensive efficacy in the treatment group was 91.4%, while it was 79. 3%in the control group, showing no statistical difference between the two groups (P > 0.05). Better effects were obtained in improving Chinese medical clinical symptoms in the treatment group (P <0.01). There was no statistical difference in the negative conversion rate between the two groups after treatment (P >0. 05). There was statistical difference in the recurrence rate between the two groups (12. 82% vs 54.76%,P <0. 05).

CONCLUSIONS

PP showed equivalent effects in treating UU infection patients of QDBSS to those of azithromycin. But PP showed obvious advantages over azithromycin in improving Chinese medical syndromes.

摘要

目的

观察盆腔炎丸治疗解脲脲原体(UU)感染气虚血瘀证患者的临床疗效。

方法

将188例UU感染气虚血瘀证患者随机分为两组,即治疗组和对照组。治疗组患者服用盆腔炎丸(每次10克,每日3次,连续服用14天为1个疗程),对照组患者服用阿奇霉素(每天1克,连续服用7天为1个疗程)。两组均连续治疗3个疗程。观察两组治疗前后的临床症状积分,判断近期疗效,并随访复发率以评估远期疗效。

结果

治疗组综合疗效总有效率为91.4%,对照组为79.3%,两组比较差异无统计学意义(P>0.05)。治疗组在改善中医临床症状方面效果更佳(P<0.01)。两组治疗后转阴率比较差异无统计学意义(P>0.05)。两组复发率比较差异有统计学意义(12.82% 对54.76%,P<0.05)。

结论

盆腔炎丸治疗UU感染气虚血瘀证患者与阿奇霉素疗效相当,但在改善中医证候方面优于阿奇霉素。

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