来自皮层下传入神经切断海马体切片中的长时程增强效应。

Long-term potentiation in slices from subcortically deafferented hippocampi.

作者信息

Czéh G, Horváth Z, Czopf J

机构信息

Institute of Physiology, University Medical School of Pécs, Hungary.

出版信息

Brain Res. 1990 Jun 4;518(1-2):279-82. doi: 10.1016/0006-8993(90)90981-g.

DOI:10.1016/0006-8993(90)90981-g

PMID:2390720

Abstract

Long-term potentiation (LTP) can be initiated in CA1, but not in the dentate, region of slices from rats with bilateral subcortical deafferentation at 8 week survival time. At about one week survival time, LTP is present in the CA1 region of all and also in the dentate of about 50% of slices. The results suggest that subcortical cholinergic and catecholaminergic inputs are not required for the LTP in the CA1 area of the rat hippocampus.

摘要

在存活8周的双侧皮层下传入神经切断的大鼠脑片中，长时程增强（LTP）可在CA1区引发，但在齿状回区域则不能引发。在存活约1周时，所有脑片的CA1区以及约50%脑片的齿状回中均存在LTP。这些结果表明，大鼠海马体CA1区的LTP不需要皮层下胆碱能和儿茶酚胺能输入。