Schneider R, Schneider C, Bänsch D
Heart Center Rostock, Department of Cardiology, University of Rostock, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany.
Herz. 2015 Feb;40(1):66-72. doi: 10.1007/s00059-013-3905-0. Epub 2013 Aug 3.
Spontaneous left atrial reentry tachycardias (LART) in patients without previous cardiac surgical or catheter ablation are rare. Several therapeutic concepts of catheter ablation have been suggested: linear lesions (LL), circumferential pulmonary vein isolation (PVI), and both (LL + PVI).
In all, 28 consecutive symptomatic patients with 51 LARTs presented to our institution for catheter ablation. Electroanatomical mapping was performed on 25 patients. Three patients were ablated conventionally during LART; 25 patients (89.3 %) had extensive low-voltage areas in the left atrium (atrial myopathy). One of the following ablation strategies was applied: first, LL (n = 8), second, PVI + LL (n = 11), and third PVI alone (n = 9). Fourteen patients (50 %) had a recurrent arrhythmia during a mean follow-up of 12.2 ± 11.1 months. Six patients presented with a recurrent LART (21.4 %), 4 with LART and atrial fibrillation (Afib) (14.3 %), and 4 with Afib (14.3 %). The recurrence rate of any arrhythmia (LART and Afib) was 37.5 % in the LL group, 44.4 % in the PVI group, and 63.6 % in the PVI + LL group (ns); the recurrence rate of LARTs was 12.5 % in the LL group, 22.2 % in the PVI group, and 63.6 % in the PVI + LL group (p < 0.05).
Atrial tachyarrhythmia recurrence after ablation of spontaneous LART in mid-term is considerable. Stable LARTs are effectively treated by LL. PVI alone may be an acceptable alternative, especially in patients with unstable LARTs and Afib. However, the risk of recurrent LARTs after a more extensive strategy with PVI and LL is considerable, probably due to proarrhythmic effects of long linear lesions.
在既往无心脏手术或导管消融史的患者中,自发性左房折返性心动过速(LART)较为罕见。已提出几种导管消融的治疗理念:线性消融(LL)、环肺静脉隔离(PVI)以及两者联合(LL + PVI)。
共有28例连续的有症状患者,伴有51次LART,前来我院接受导管消融治疗。对25例患者进行了电解剖标测。3例患者在LART发作时进行了传统消融;25例患者(89.3%)左房存在广泛的低电压区(心房心肌病)。采用了以下消融策略之一:首先,LL(n = 8);其次,PVI + LL(n = 11);第三,单纯PVI(n = 9)。在平均12.2±11.1个月的随访期间,14例患者(50%)出现心律失常复发。6例患者复发LART(21.4%),4例患者复发LART并伴有房颤(Afib)(14.3%),4例患者复发Afib(14.3%)。LL组任何心律失常(LART和Afib)的复发率为37.5%,PVI组为44.4%,PVI + LL组为63.6%(无统计学差异);LART的复发率在LL组为12.5%,PVI组为22.2%,PVI + LL组为63.6%(p < 0.05)。
中期消融自发性LART后房性快速性心律失常复发情况较为可观。稳定的LART可通过LL有效治疗。单纯PVI可能是一种可接受的替代方法,尤其是对于不稳定LART和Afib患者。然而,采用更广泛的PVI和LL策略后LART复发风险较高,可能是由于长线性消融的促心律失常作用。