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[半皮质骨切除及重建术用于低级别恶性骨肿瘤的挽救性治疗]

[Salvage therapy by hemicortical excision and reconstruction for low-grade malignant bone tumour].

作者信息

Zhang Qing, Liu Tang, Guo Xiaoning, Ling Lin

机构信息

Department of Orthopedics, Second Xiangya Hospital, Central South University, Changsha 410011, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Jul;38(7):691-4. doi: 10.3969/j.issn.1672-7347.2013.07.007.

DOI:10.3969/j.issn.1672-7347.2013.07.007
PMID:23908087
Abstract

OBJECTIVE

To treat low-grade limb malignant tumors with hemicortical excision and reconstruction of the defect with recycled pasteurized autograft.

METHODS

From January 2005 to January 2011, 10 patients [age (27.0±6.5) years] suffering from low-grade limb malignant tumors were treated with hemicortical excision and reconstruction of the defect with recycled pasteurized autograft: 7 were histopathologically diagnosed as parosteal osteosarcoma, and 3 as peripheral chondrosarcoma. According to the Enneking staging system, 8 were in Stage IA and 2 were in IB.

RESULTS

All the patients were followed-up for (50±23) months. All the patients had bony union at the last follow-up. The length of tumor bone resection was (9.5±2.7) cm, operation time was (150±45) min, intraoperative blood loss was (1000±350) mL, and drainage volume was (450±200) mL. The only fracture in the host bone during the operation was treated by internal fixation. Local recurrence occurred in 1 patient was treated by a wide operative margin and reconstruction with a prosthesis. There was no distal metastasis. A ccording to the Enneking system, 9 patients had excellent results and 1 had good results.

CONCLUSION

Hemicortical excision for low-grade limb malignant tumors is safe and effective.

摘要

目的

采用半皮质骨切除及回植经巴氏消毒的自体移植骨重建缺损来治疗肢体低度恶性肿瘤。

方法

2005年1月至2011年1月,10例[年龄(27.0±6.5)岁]肢体低度恶性肿瘤患者接受了半皮质骨切除及回植经巴氏消毒的自体移植骨重建缺损治疗:组织病理学诊断7例为骨旁骨肉瘤,3例为外周型软骨肉瘤。根据Enneking分期系统,8例为IA期,2例为IB期。

结果

所有患者均获(50±23)个月的随访。末次随访时所有患者均获骨愈合。肿瘤骨切除长度为(9.5±2.7)cm,手术时间为(150±45)分钟,术中失血量为(1000±350)mL,引流量为(450±200)mL。术中发生的1例宿主骨骨折采用内固定治疗。1例局部复发患者行扩大手术切除边缘并用假体重建。无远处转移。根据Enneking系统,9例患者效果优良,1例效果良好。

结论

肢体低度恶性肿瘤行半皮质骨切除安全有效。

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[Salvage therapy by hemicortical excision and reconstruction for low-grade malignant bone tumour].[半皮质骨切除及重建术用于低级别恶性骨肿瘤的挽救性治疗]
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Jul;38(7):691-4. doi: 10.3969/j.issn.1672-7347.2013.07.007.
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Hemicortical resection and reconstruction using pasteurised autograft for parosteal osteosarcoma of the distal femur.采用巴氏消毒的自体移植物进行半皮质切除术和重建治疗股骨远端骨旁骨肉瘤。
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Hemicortical excision for low-grade selected surface sarcomas of bone.对选定的低度骨表面肉瘤进行半皮质切除术。
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