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唐氏综合征患者唾液腺先天缺失。

Congenital absence of salivary glands in Down syndrome.

机构信息

Department of Obstetrics and Gynecology, Western Galilee Hospital, , Nahariya, Israel.

出版信息

Arch Dis Child. 2013 Oct;98(10):781-3. doi: 10.1136/archdischild-2013-303841. Epub 2013 Aug 1.

DOI:10.1136/archdischild-2013-303841
PMID:23908188
Abstract

BACKGROUND

Children with Down syndrome have different saliva composition compared to normal children. The presence or absence of the salivary glands has not been previously reported.

OBJECTIVE

To examine the presence or absence of the salivary glands in children with Down syndrome.

METHODS

15 children with Down syndrome underwent an ultrasound examination of the salivary glands. The control group consisted of 31 healthy children. The areas of the parotid and submandibular glands on both sides were scanned in an attempt to demonstrate all four glands. The result was reported as 'present' or 'absent'.

RESULTS

In four children out of 15 with Down syndrome, one or more salivary glands were absent (26.7%), while in the controls all salivary glands were present. The difference between the groups was statistically significant (p=0.008). There was no significant difference between the groups regarding age and sex.

CONCLUSIONS

At least one salivary gland is undetected by ultrasound in some children with Down syndrome.

摘要

背景

唐氏综合征患儿的唾液成分与正常儿童不同。目前尚未有关于唾液腺是否存在的报道。

目的

检查唐氏综合征患儿唾液腺的存在情况。

方法

对 15 名唐氏综合征患儿进行唾液腺超声检查。对照组由 31 名健康儿童组成。尝试对双侧腮腺和颌下腺进行扫描,以显示所有四个腺体。结果报告为“存在”或“缺失”。

结果

在 15 名唐氏综合征患儿中,有 4 名(26.7%)患儿存在一个或多个唾液腺缺失,而对照组所有患儿的唾液腺均存在。两组间差异具有统计学意义(p=0.008)。两组间在年龄和性别方面无显著差异。

结论

在一些唐氏综合征患儿中,至少有一个唾液腺在超声检查中未被检测到。

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