持续性囊性纤维化分离株铜绿假单胞菌RP73的全基因组序列
Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73.
作者信息
Jeukens Julie, Boyle Brian, Bianconi Irene, Kukavica-Ibrulj Irena, Tümmler Burkhard, Bragonzi Alessandra, Levesque Roger C
机构信息
Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Quebec, Canada.
出版信息
Genome Announc. 2013 Aug 1;1(4):e00568-13. doi: 10.1128/genomeA.00568-13.
Abstract
Pseudomonas aeruginosa can establish lifelong chronic airway infections in cystic fibrosis (CF) patients. However, the genetic features associated with long-term persistence in the lung are not understood. We sequenced the genome of P. aeruginosa strain RP73, which was isolated after 16.9 years of chronic lung infection in a CF patient.
摘要
铜绿假单胞菌可在囊性纤维化（CF）患者中引发终身性慢性气道感染。然而，与在肺部长期持续存在相关的基因特征尚不清楚。我们对铜绿假单胞菌RP73菌株的基因组进行了测序，该菌株是从一名CF患者慢性肺部感染16.9年后分离得到的。
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