Lee A W, Cheng L O, Ng S H, Tse V K, O S K, Au G K, Poon Y F
Medical and Health Department Institute of Radiology and Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Clin Radiol. 1990 Jul;42(1):24-31. doi: 10.1016/s0009-9260(05)81617-4.
Magnetic resonance imaging (MRI) and computed tomography (CT) were performed on 13 patients with clinical features of late temporal lobe damage following radical radiotherapy for nasopharyngeal carcinoma, and their results compared. MRI was undoubtedly superior in sensitivity--revealing areas of prolonged T2 relaxation time in the inferior portions of the temporal lobes in all patients, while CT failed to show any gross abnormalities in seven. In patients with large lesions well-depicted on CT, the corresponding MRI changes were comparable in shape and extent. But MRI gave an additional sign for the presence of liquefactive necrosis, and revealed lesions in the contralateral lobes in two out of three patients with unilateral CT changes. Besides obvious improvement in detection rate, the contribution of MRI to the better selection of treatment protocols, and to the understanding of the pathological process are discussed.
对13例鼻咽癌根治性放疗后出现晚期颞叶损伤临床特征的患者进行了磁共振成像（MRI）和计算机断层扫描（CT）检查，并对结果进行了比较。MRI在敏感性方面无疑更具优势——所有患者颞叶下部均显示T2弛豫时间延长区域，而7例患者的CT未显示任何明显异常。在CT清晰显示大病灶的患者中，相应的MRI改变在形状和范围上具有可比性。但MRI给出了液化性坏死存在的额外征象，并且在3例单侧CT改变的患者中有2例在对侧叶发现了病变。除了检测率有明显提高外，还讨论了MRI在更好地选择治疗方案以及理解病理过程方面的作用。
