Templeton Alan R
Departments of Biology and Genetics, Washington University, St. Louis, Missouri, USA; Department of Evolutionary and Environmental Biology, University of Haifa, Israel.
Rambam Maimonides Med J. 2010 Jul 2;1(1):e0006. doi: 10.5041/RMMJ.10006. Print 2010 Jul.
It has been argued that human evolution has stopped because humans now adapt to their environment via cultural evolution and not biological evolution. However, all organisms adapt to their environment, and humans are no exception. Culture defines much of the human environment, so cultural evolution has actually led to adaptive evolution in humans. Examples are given to illustrate the rapid pace of adaptive evolution in response to cultural innovations. These adaptive responses have important implications for infectious diseases, Mendelian genetic diseases, and systemic diseases in current human populations. Moreover, evolution proceeds by mechanisms other than natural selection. The recent growth in human population size has greatly increased the reservoir of mutational variants in the human gene pool, thereby enhancing the potential for human evolution. The increase in human population size coupled with our increased capacity to move across the globe has induced a rapid and ongoing evolutionary shift in how genetic variation is distributed within and among local human populations. In particular, genetic differences between human populations are rapidly diminishing and individual heterozygosity is increasing, with beneficial health effects. Finally, even when cultural evolution eliminates selection on a trait, the trait can still evolve due to natural selection on other traits. Our traits are not isolated, independent units, but rather are integrated into a functional whole, so selection on one trait can cause evolution to occur on another trait, sometimes with mildly maladaptive consequences.
有人认为人类进化已经停止,因为人类现在是通过文化进化而非生物进化来适应环境。然而,所有生物都会适应环境,人类也不例外。文化在很大程度上定义了人类环境,所以文化进化实际上导致了人类的适应性进化。文中给出了一些例子来说明人类对文化创新做出的适应性进化的快速步伐。这些适应性反应对当前人类群体中的传染病、孟德尔遗传病和全身性疾病具有重要意义。此外,进化是通过自然选择以外的机制进行的。最近人类人口规模的增长极大地增加了人类基因库中突变变体的储备,从而增强了人类进化的潜力。人类人口规模的增加以及我们在全球范围内移动能力的增强,引发了遗传变异在当地人群内部和之间分布方式的快速且持续的进化转变。特别是,人群之间的遗传差异正在迅速缩小,个体杂合性正在增加,这对健康有益。最后,即使文化进化消除了对某一性状的选择,由于对其他性状的自然选择,该性状仍可能进化。我们的性状不是孤立、独立的单位,而是整合为一个功能整体,所以对一个性状的选择会导致另一个性状发生进化,有时会产生轻度适应不良的后果。