School of Biology, University of St Andrews, Bute Building, Westburn Lane, St Andrews, Fife KY16 9TS, UK.
Nat Rev Genet. 2010 Feb;11(2):137-48. doi: 10.1038/nrg2734.
Researchers from diverse backgrounds are converging on the view that human evolution has been shaped by gene-culture interactions. Theoretical biologists have used population genetic models to demonstrate that cultural processes can have a profound effect on human evolution, and anthropologists are investigating cultural practices that modify current selection. These findings are supported by recent analyses of human genetic variation, which reveal that hundreds of genes have been subject to recent positive selection, often in response to human activities. Here, we collate these data, highlighting the considerable potential for cross-disciplinary exchange to provide novel insights into how culture has shaped the human genome.
来自不同背景的研究人员正在达成这样一种共识，即人类进化受到了基因-文化相互作用的影响。理论生物学家利用群体遗传学模型证明了文化过程可以对人类进化产生深远的影响，而人类学家则在研究改变当前选择的文化实践。这些发现得到了人类遗传变异的最新分析的支持，这些分析揭示了数百个基因已经受到了近期的正向选择，这通常是对人类活动的反应。在这里，我们整理了这些数据，突出了跨学科交流的巨大潜力，以提供关于文化如何塑造人类基因组的新见解。
