Sever Mehmet Sukru, Vanholder Raymond
Local co-ordinator for the Renal Disaster Relief Task Force of the International Society of Nephrology (ISN); Department of Internal Medicine/Nephrology, Istanbul School of Medicine, Istanbul, Turkey, and.
Rambam Maimonides Med J. 2011 Apr 30;2(2):e0039. doi: 10.5041/RMMJ.10039. Print 2011 Apr.
After direct impact of the trauma, crush syndrome is the second most frequent cause of death after mass disasters. However, since crush syndrome is quite rare in daily practice, mistakes are frequent in the treatment of these cases. This paper summarizes the etiopathogenesis of traumatic rhabdomyolysis and of crush syndrome-based acute kidney injury. The clinical and laboratory features, prophylaxis, and treatment of crush cases are described as well. The importance of early and energetic fluid resuscitation is underlined for prophylaxis of acute kidney injury. Since there is chaos, and an overwhelming number of victims, logistic drawbacks create a specific problem in the treatment of crush victims after mass disasters. Potential solutions for logistic hurdles and disaster preparedness scenarios have also been provided in this review article.
在创伤直接冲击后,挤压综合征是大规模灾难后第二常见的死亡原因。然而,由于挤压综合征在日常实践中相当罕见,这些病例的治疗中经常出现错误。本文总结了创伤性横纹肌溶解症和基于挤压综合征的急性肾损伤的发病机制。还描述了挤压病例的临床和实验室特征、预防措施及治疗方法。强调了早期积极液体复苏对预防急性肾损伤的重要性。由于混乱以及受害者数量众多,后勤保障方面的缺陷在大规模灾难后挤压受害者的治疗中造成了一个特殊问题。这篇综述文章还提供了应对后勤障碍和灾难准备预案的潜在解决方案。