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良性起病的急性播散性脑脊髓炎:两例报告

Benign-onset acute disseminated encephalomyelitis: a report on two cases.

作者信息

Degirmenci Eylem, Erdogan Cagdas, Oguzhanoglu Attila, Bir Levent Sinan

机构信息

Pamukkale University, Faculty of Medicine, Neurology Department, Denizli, Turkey.

出版信息

Ideggyogy Sz. 2013 May 30;66(5-6):196-9.

PMID:23909020
Abstract

The signs and symptoms of acute disseminated encephalomyelitis are heterogeneous and dependent on the location and severity of the inflammatory process. The meningoencephalitic presentation may include meningism, impaired consciousness (occasionally leading to coma), seizures and confusion, or behavioral disturbances. Multifocal neurological features include a combination of optic neuritis, visual field defects, cranial neuropathy, sensorimotor impairment, ataxia, aphasia, and involuntary movements. One definition of acute disseminated encephalomyelitis is "an initial clinical event with a presumed inflammatory and demyelinating cause, with acute or sub-acute onset affecting multifocal areas of the central nervous system". Patients with acute disseminated encephalomyelitis frequently suffer from seizures, disturbances of consciousness, fever, and headaches, and occasionally there are focal signs and symptoms. Here, we report on two cases who presented with different symptoms, but the clinical findings that the patients showed were benign.

摘要

急性播散性脑脊髓炎的体征和症状具有异质性,取决于炎症过程的部位和严重程度。脑膜脑炎表现可能包括脑膜刺激征、意识障碍(偶尔导致昏迷)、癫痫发作、意识模糊或行为障碍。多灶性神经功能特征包括视神经炎、视野缺损、颅神经病变、感觉运动障碍、共济失调、失语和不自主运动等多种表现。急性播散性脑脊髓炎的一种定义是“一种初始临床事件,推测由炎症和脱髓鞘原因引起,急性或亚急性起病,累及中枢神经系统的多灶性区域”。急性播散性脑脊髓炎患者常伴有癫痫发作、意识障碍、发热和头痛,偶尔还会出现局灶性体征和症状。在此,我们报告两例表现出不同症状但临床检查结果为良性的病例。

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