Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Oncology (Williston Park). 2013 Jun;27(6):526-7, 566.
This is a young premenopausal woman with a T1cN0 metaplastic breast cancer that is ER/PR Allred score 3, but negative by mRNA. Our recommendations are: adjuvant chemotherapy with TAC x 6 or dose-dense doxorubicin and cyclophosphamide followed by paclitaxel (ddAC-T). Whole-breast radiation therapy would follow. The patient could try tamoxifen, although the likelihood of benefit is very small.
这是一位年轻绝经前女性，患有 T1cN0 型化生性乳腺癌，ER/PR Allred 评分为 3 分，但 mRNA 为阴性。我们的建议是：TAC 方案（表柔比星、多西他赛、环磷酰胺）化疗 6 周期，或密集型多柔比星和环磷酰胺序贯紫杉醇（ddAC-T）化疗。然后行全乳放疗。患者可以尝试服用他莫昔芬，但获益的可能性很小。
