Adeyeye O O, Ogunleye O O, Onadeko B O, Bamisile R T, Brodie-Mends A, Ekrikpo U
Department of Medicine, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria.
Afr J Med Med Sci. 2013 Mar;42(1):33-8.
Asthma and obesity have considerable impact on public health. There is increase prevalence of both conditions worldwide. This study was undertaken to determine the prevalence of obesity among asthma patients as well as determine the effect of body mass index (BMI) on asthma severity and pulmonary functions.
The study was conducted at the asthma clinic of the medical outpatient of Lagos State University Teaching Hospital, Ikeja. Ethical clearance was obtained from the hospital's research and ethics committee. Non probability sampling method was used with consecutive asthma patients diagnosed by the respiratory physicians according to NHLBI guideline recruited into the study. The weight, height and pulmonary function tests were carried out using standard methods. Acarefully designed interviewer administered questionnaire were used to collect information on the socio demographic characteristics of the patient, asthma symptoms, control use of rescue medications and emergency visits.
One hundred and fifty eight (158) asthma patients participated in the study. There were 63 (39.9%) males and 95 (60.1%) females. The prevalence of obesity was 53.8%. The mean age of respondents was 46.48 +/- 17.16 years. Age, educational level and employment status were related to the body mass index while gender and duration of asthma were not. There was no difference in the severity of asthma and utilization of emergency services across the BMI categories. The obese asthmatics generally recorded lower lung function volumes compared with the non-obese asthmatic groups.
Prevalence of obesity is high among the asthmatics studied. There is no difference in asthma severity across the BMI categories. Pulmonary functions are lower in obese asthmatics.
哮喘和肥胖对公众健康有重大影响。全球范围内这两种疾病的患病率均在上升。本研究旨在确定哮喘患者中肥胖的患病率，并确定体重指数（BMI）对哮喘严重程度和肺功能的影响。
本研究在拉各斯州立大学教学医院伊凯贾分院的内科门诊哮喘诊所进行。获得了医院研究与伦理委员会的伦理批准。采用非概率抽样方法，根据美国国立心肺血液研究所（NHLBI）指南，由呼吸内科医生连续诊断的哮喘患者被纳入研究。使用标准方法进行体重、身高和肺功能测试。通过精心设计的由访谈者管理的问卷收集患者的社会人口统计学特征、哮喘症状、急救药物的使用情况和急诊就诊信息。
158名哮喘患者参与了本研究。其中男性63名（39.9%），女性95名（60.1%）。肥胖患病率为53.8%。受访者的平均年龄为46.48±17.16岁。年龄、教育程度和就业状况与体重指数有关，而性别和哮喘病程则无关。不同BMI类别之间哮喘严重程度和急诊服务利用情况无差异。与非肥胖哮喘组相比，肥胖哮喘患者的肺功能指标通常较低。
在所研究的哮喘患者中肥胖患病率较高。不同BMI类别之间哮喘严重程度无差异。肥胖哮喘患者的肺功能较低。
