Ahmadiafshar Akefeh, Tabbekhha Sara, Mousavinasab Noureddin, Khoshnevis Parisa
Metabolic Diseases Research Center, AND Pediatric Ward, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran.
Acta Med Iran. 2013;51(9):615-9.
Childhood asthma and obesity are significant public health problems. Most prospective studies suggest that obesity increases the risk of asthma. But, some authors did not found this association. In this study the association between asthma and body mass index (BMI) was investigated. This case-control study was conducted on 200 asthmatic children aged 6-15 years and 200 children without asthma. The criteria for asthma diagnosis and its classification were on the basis of National Asthma Education and Prevention Program (NAEPP). BMI of patients and controls were also measured and BMI grater than 85% and 95% were defined as overweight and obese respectively. The data was analyzed by SPSS software. The BMI among the asthmatic children (17.9 kg/m2) was higher than the BMI among the non-asthmatics (16.5 kg/m2), P=0.0001. This relationship was significant in both males and females. 18% of asthmatic children were classified as overweight and 13.5% of them were obese versus 7.5% and 6% respectively in non asthmatics (P=0.0001). However, there was no significant relationship between severity, duration of asthma, kind of medication and BMI in children with asthma (P>0.05). Result of this study showed that there is an association between asthma symptoms and obesity in children. Therefore, any attempts for weight control in asthmatic children might be beneficial.
儿童哮喘和肥胖是重大的公共卫生问题。大多数前瞻性研究表明，肥胖会增加患哮喘的风险。但是，一些作者并未发现这种关联。在本研究中，对哮喘与体重指数（BMI）之间的关联进行了调查。这项病例对照研究针对200名6至15岁的哮喘儿童和200名无哮喘儿童展开。哮喘诊断标准及其分类依据国家哮喘教育与预防计划（NAEPP）。还测量了患者和对照组的BMI，BMI大于85%和95%分别被定义为超重和肥胖。数据采用SPSS软件进行分析。哮喘儿童的BMI（17.9kg/m²）高于非哮喘儿童的BMI（16.5kg/m²），P=0.0001。这种关系在男性和女性中均具有显著性。18%的哮喘儿童被归类为超重，13.5%的哮喘儿童被归类为肥胖，而非哮喘儿童的这一比例分别为7.5%和6%（P=0.0001）。然而，哮喘的严重程度、病程、药物种类与哮喘儿童的BMI之间没有显著关系（P>0.05）。本研究结果表明，儿童哮喘症状与肥胖之间存在关联。因此，对哮喘儿童进行任何体重控制的尝试可能都是有益的。
