Krechler T, Ulrych J, Dvořák M, Hoskovec D, Macášek J, Švestka T, Hořejš J
IV. interní klinika - klinika gastroenterologie a hepatologie 1. lékařské fakulty UK a VFN Praha.
Vnitr Lek. 2013 Jul;59(7):572-7.
Number of newly diagnosed cystic pancreatic tumors is permanently increasing. This fact is primarily related to the development of new diagnostic methods. The main representative ones are: serous cystadenoma, mucinous cystic neoplasm, intraductal papillary mucinous neoplasm and solid pseudopapillar tumor. Because of the malignant potential of these lesions, proper indication of surgical treatment is extremely important. The article highlights and describes our experience in diagnostics and therapy of cystic pancreatic tumors diagnosed in the General Teaching Hospital Prague in the period: 1/ 2008- 12/ 2012. All patients were investigated by computerised tomography and endoscopic ultrasound with fine - needle aspiration biopsy. Thirty seven patients in total were diagnosed with cystic pancreatic tumors: 19 with serous cystadenoma, 5 with mucinous cystic neoplasm, 5 with mucinous cystadenocarcinoma, 5 with intraductal papillary mucinous neoplasm and 3 with solid pseudopapillar tumor. In 14 cases patients were indicated for surgery, in 1 case signs of malignant transformation were found. Determination of the optimal strategy for diagnostic and therapeutic procedures in patients with cystic pancreatic tumors requires the dia-gnosis, treatment and followup observation in adequately equiped specialized centers.
新诊断出的胰腺囊性肿瘤数量一直在增加。这一事实主要与新诊断方法的发展有关。主要的代表性肿瘤有:浆液性囊腺瘤、黏液性囊性肿瘤、导管内乳头状黏液性肿瘤和实性假乳头状肿瘤。由于这些病变具有恶变潜能,正确的手术治疗指征极为重要。本文着重介绍并描述了我们在2008年1月至2012年12月期间于布拉格综合教学医院诊断和治疗胰腺囊性肿瘤的经验。所有患者均接受了计算机断层扫描和内镜超声引导下细针穿刺活检。共有37例患者被诊断为胰腺囊性肿瘤:19例浆液性囊腺瘤、5例黏液性囊性肿瘤、5例黏液性囊腺癌、5例导管内乳头状黏液性肿瘤和3例实性假乳头状肿瘤。14例患者有手术指征,1例发现恶变迹象。确定胰腺囊性肿瘤患者诊断和治疗程序的最佳策略需要在设备齐全的专业中心进行诊断、治疗和随访观察。