Department of Medicine, New York University School of Medicine, New York, NY; North Shore University Hospital-Long Island Jewish Health System, Manhasset, NY; and St Francis Hospital, Roslyn, NY.
Mayo Clin Proc. 2013 Aug;88(8):841-53. doi: 10.1016/j.mayocp.2013.05.001.
Ulcerative colitis diagnosis and management represent a challenge for clinicians. The disguises of ischemia and acute infectious colitis continue to confound the diagnosis. The therapeutic options have remarkably expanded in the way of immunomodulators, biologics, or ileoanal pouch surgery, yet all carry potential considerable risks. These risks can confuse and impair patient acceptance, particularly elderly patients and men younger than 30 years. Predictors of outcome of medical and surgical therapy have improved but are far from complete. Nevertheless, therapies focused on the specific patient's condition continue to offer hope.
溃疡性结肠炎的诊断和治疗对临床医生来说是一个挑战。缺血和急性感染性结肠炎的表现形式仍使诊断变得复杂。治疗选择在免疫调节剂、生物制剂或回肠直肠袋手术方面有了显著的扩展,但所有这些都有潜在的重大风险。这些风险可能会使患者,特别是老年患者和 30 岁以下的男性,感到困惑并影响他们的接受程度。医疗和手术治疗的预后预测指标有所改善,但还远未完善。尽管如此,针对特定患者病情的治疗方法仍有希望。