Yeager Harold K, Ignaut Debra A
Eli Lilly and Company, Lilly Corporate Center DC, Indianapolis, IN 46285, USA.
J Diabetes Sci Technol. 2013 Jul 1;7(4):1027-9. doi: 10.1177/193229681300700427.
Pen injectors for the administration of insulin have been available since the 1980s. The first insulin pen, NovoPen®, was introduced by Novo in 1985 (http://www.novonordisk.com/about_us/history/step-by-step.asp). In the years since, insulin pens have seen innovation in both features and functionality, and many more manufacturers have entered the market. This analysis discusses several features and design alternatives of insulin pens and comments on a new study by Bohnet and coauthors in this issue of Journal of Diabetes Science and Technology that compared the dosing accuracy of the spring-driven FlexTouch® (FT; Novo Nordisk; insulin aspart) with that of the manually operated SoloSTAR® (Sanofi; insulin glulisine). The volumetric flow rate of insulin delivery with FT was also evaluated.
自20世纪80年代以来,就有用于注射胰岛素的笔式注射器。第一支胰岛素笔诺和笔®由诺和诺德公司于1985年推出(http://www.novonordisk.com/about_us/history/step-by-step.asp)。从那以后的几年里,胰岛素笔在功能和特性方面都有了创新,更多的制造商进入了这个市场。本分析讨论了胰岛素笔的几个特性和设计选择,并对Bohnet及其合著者在本期《糖尿病科学与技术杂志》上的一项新研究进行了评论,该研究比较了弹簧驱动的FlexTouch®(FT;诺和诺德公司;门冬胰岛素)和手动操作的SoloSTAR®(赛诺菲;赖脯胰岛素)的给药准确性。还评估了FT输送胰岛素的体积流速。