Yamashita Yukimasa, Fukushima Masashi, Sumitomo Yasuhiko, Son Yongi, Maruo Masayuki, Itai Ryosuke, Ono Hiroshi, Kimura Yoshito, Ikeda Eiji, Takada Mariko, Mikami Sakae, Nishigami Takayuki
Department of Gastroenterology, Kobe City Medical Center West Hospital, Japan.
Nihon Shokakibyo Gakkai Zasshi. 2013 Aug;110(8):1454-60.
A 55-year-old man presented at our hospital with a large polypoid esophageal tumor. Initial upper gastrointestinal endoscopy revealed that this tumor had sloughed off to be replaced with ulceration in the thoracic esophagus. However, after the tumor at the thoracic esophagus sloughed off, a semi-circular, superficial, flat squamous cell carcinoma was observed adjacent to the ulceration. In addition, a separate carcinosarcoma, 2cm in diameter, was found at the esophagogastric junction. Approximately one month later, endoscopic re-examination revealed a new polypoid tumor approximately 4cm in diameter that was growing rapidly in the center of the superficial thoracic esophageal carcinoma lesion. Standard subtotal esophagectomy was performed. Histopathological examination revealed that both lesions were esophageal carcinosarcomas. This is a rare case of double esophageal carcinosarcoma associated with rapid polypoid tumor growth from a superficial squamous cell carcinoma lesion.
一名55岁男性因巨大息肉样食管肿瘤就诊于我院。初次上消化道内镜检查发现,该肿瘤已脱落,胸段食管出现溃疡。然而,胸段食管肿瘤脱落后,在溃疡旁观察到一个半圆形、浅表、扁平的鳞状细胞癌。此外,在食管胃交界处发现一个直径2cm的独立癌肉瘤。大约一个月后,内镜复查发现一个直径约4cm的新息肉样肿瘤,在胸段食管浅表癌病变中心迅速生长。遂行标准食管次全切除术。组织病理学检查显示,两个病变均为食管癌肉瘤。这是一例罕见的双发性食管肉瘤,伴有浅表鳞状细胞癌病变快速生长出息肉样肿瘤。