College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Fitoterapia. 2013 Oct;90:185-91. doi: 10.1016/j.fitote.2013.07.013. Epub 2013 Jul 31.
Four new dammarane-type triterpene glycosides, named jujubosides I-IV (1-4), were isolated from Ziziphi Spinosae Semen, along with seven known saponins (5-11). The structures of new compounds were established on the basis of extensive spectroscopic analysis. All compounds were evaluated for the effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide in vitro.
从酸枣仁中分离得到四种新的达玛烷型三萜皂苷,分别命名为酸枣仁皂苷 I-IV(1-4),并结合七种已知的皂苷(5-11)。新化合物的结构是基于广泛的光谱分析确定的。所有化合物均进行了体外评估,以考察其对过氧化氢诱导的新生大鼠心肌细胞损伤的影响。