Am J Gastroenterol. 2013 Aug;108(8):1341-3. doi: 10.1038/ajg.2013.177.
While colonoscopy is the gold standard for the evaluation of the colon, research on post-colonoscopy colorectal cancers has increased our awareness of its limitations. In this issue of the Journal, Erichsen et al. provide evidence to suggest that post-colonoscopy colorectal cancers are most likely due to missed cancers at the time of the index colonoscopy, rather than due to aggressive tumor biology. Ultimately, studies demonstrating the shortcomings of colonoscopy are a call to action for the gastroenterology community to develop strategies and new technologies to improve the effectiveness of colonoscopy.
虽然结肠镜检查是评估结肠的金标准,但对结肠镜检查后的结直肠癌的研究增加了我们对其局限性的认识。在本期杂志中,Erichsen 等人提供的证据表明,结肠镜检查后的结直肠癌很可能是由于在进行索引结肠镜检查时漏诊了癌症,而不是由于肿瘤的侵袭性生物学特性所致。最终,这些表明结肠镜检查存在缺陷的研究呼吁消化病学领域制定策略和新技术,以提高结肠镜检查的效果。