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Maintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine.

作者信息

Maeda T, Hosen N, Fukushima K, Tsuboi A, Morimoto S, Matsui T, Sata H, Fujita J, Hasegawa K, Nishida S, Nakata J, Nakae Y, Takashima S, Nakajima H, Fujiki F, Tatsumi N, Kondo T, Hino M, Oji Y, Oka Y, Kanakura Y, Kumanogoh A, Sugiyama H

机构信息

Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.

出版信息

Blood Cancer J. 2013 Aug 2;3(8):e130. doi: 10.1038/bcj.2013.29.

DOI:10.1038/bcj.2013.29
PMID:23912610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3763383/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d13b/3763383/cf426cbf326c/bcj201329f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d13b/3763383/cf426cbf326c/bcj201329f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d13b/3763383/cf426cbf326c/bcj201329f1.jpg

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Maintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine.
Blood Cancer J. 2013 Aug 2;3(8):e130. doi: 10.1038/bcj.2013.29.
2
The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study.亲缘供者异基因造血干细胞移植在儿科高危急性髓系白血病中的作用：来自 AML-BFM 98 研究的结果。
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4
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Hum Vaccin Immunother. 2024 Dec 31;20(1):2296735. doi: 10.1080/21645515.2023.2296735. Epub 2023 Dec 26.
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WT1 epitope-specific IgG and IgM antibodies for immune-monitoring in patients with advanced sarcoma treated with a WT1 peptide cancer vaccine.

本文引用的文献

1
Long-term WT1 peptide vaccination for patients with acute myeloid leukemia with minimal residual disease.针对伴有微小残留病的急性髓系白血病患者的长期WT1肽疫苗接种。
Leukemia. 2012 Jun;26(6):1410-3. doi: 10.1038/leu.2011.343. Epub 2011 Dec 13.
2
Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies.髓系恶性肿瘤患者接受PR1和WT1肽联合疫苗接种后的白血病相关抗原特异性T细胞反应。
Blood. 2008 Jan 1;111(1):236-42. doi: 10.1182/blood-2007-08-108241. Epub 2007 Sep 17.
3
Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.
用于接受WT1肽癌症疫苗治疗的晚期肉瘤患者免疫监测的WT1表位特异性IgG和IgM抗体。
Oncol Lett. 2022 Feb;23(2):65. doi: 10.3892/ol.2022.13184. Epub 2022 Jan 3.
4
Prevention and Treatment of Acute Myeloid Leukemia Relapse after Hematopoietic Stem Cell Transplantation: The State of the Art and Future Perspectives.造血干细胞移植后急性髓系白血病复发的防治：现状与未来展望
J Clin Med. 2022 Jan 4;11(1):253. doi: 10.3390/jcm11010253.
5
Identification of mouse helper epitopes for WT1-specific CD4 T cells.鉴定 WT1 特异性 CD4 T 细胞的小鼠辅助表位。
Cancer Immunol Immunother. 2021 Nov;70(11):3323-3335. doi: 10.1007/s00262-021-03003-5. Epub 2021 Jul 16.
6
Immunotherapy in Acute Myeloid Leukemia: Where We Stand.急性髓系白血病的免疫治疗：现状
Front Oncol. 2021 May 10;11:656218. doi: 10.3389/fonc.2021.656218. eCollection 2021.
7
Redirecting the Immune Microenvironment in Acute Myeloid Leukemia.重定向急性髓系白血病中的免疫微环境
Cancers (Basel). 2021 Mar 20;13(6):1423. doi: 10.3390/cancers13061423.
8
Maintenance therapy in acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation.异基因造血干细胞移植后急性髓系白血病的维持治疗。
J Hematol Oncol. 2021 Jan 6;14(1):4. doi: 10.1186/s13045-020-01017-7.
9
Induction of anti-leukemic responses by stimulation of leukemic CD3+ cells with allogeneic stimulator cells.通过用同种异体刺激细胞刺激白血病CD3 +细胞诱导抗白血病反应。
Exp Hematol Oncol. 2018 Oct 4;7:25. doi: 10.1186/s40164-018-0118-5. eCollection 2018.
10
TGF-β1-silenced leukemia cell-derived exosomes target dendritic cells to induce potent anti-leukemic immunity in a mouse model.TGF-β1沉默的白血病细胞衍生外泌体靶向树突状细胞，在小鼠模型中诱导强大的抗白血病免疫。
Cancer Immunol Immunother. 2017 Oct;66(10):1321-1331. doi: 10.1007/s00262-017-2028-5. Epub 2017 Jun 10.
WT1（威尔姆斯瘤基因）肽疫苗诱导WT1特异性细胞毒性T淋巴细胞及由此导致的癌症消退。
Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13885-90. doi: 10.1073/pnas.0405884101. Epub 2004 Sep 13.
4
Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues.用在HLA - A*2402结合残基处修饰的9聚体WT1肽增强人WT1特异性细胞毒性T淋巴细胞的诱导。
Cancer Immunol Immunother. 2002 Dec;51(11-12):614-20. doi: 10.1007/s00262-002-0328-9. Epub 2002 Oct 18.
5
Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients.通过实时定量聚合酶链反应对WT1表达进行定量评估，可能是监测急性白血病患者微小残留病的一种有用工具。
Leukemia. 2002 Oct;16(10):2115-21. doi: 10.1038/sj.leu.2402675.
6
WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia.WT1作为急性白血病新的预后因素及微小残留病检测的新标志物。
Blood. 1994 Nov 1;84(9):3071-9.
7
Expression of the Wilms' tumor gene (WT1) in human leukemias.威尔姆斯瘤基因（WT1）在人类白血病中的表达。
Leukemia. 1992 May;6(5):405-9.
8
Antileukemic effect of graft-versus-host disease in human recipients of allogeneic-marrow grafts.异基因骨髓移植受者中移植物抗宿主病的抗白血病效应
N Engl J Med. 1979 May 10;300(19):1068-73. doi: 10.1056/NEJM197905103001902.