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老年男性膀胱过度活动症:流行病学、评估、临床影响和管理。

Overactive bladder in elderly men: epidemiology, evaluation, clinical effects, and management.

机构信息

Department of Urology and The Landon Center on Aging, The University of Kansas School of Medicine, Mailstop 3016, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA,

出版信息

Curr Urol Rep. 2013 Oct;14(5):418-25. doi: 10.1007/s11934-013-0367-0.

DOI:10.1007/s11934-013-0367-0
PMID:23913201
Abstract

Overactive bladder (OAB) is a highly prevalent clinical condition in both men and women, and rates tend to increase with advancing age. A variety of different evaluation methods have been developed to measure both objective and subjective parameters of the condition. OAB has been associated with negative clinical outcomes, particularly in older adults, including depression, social isolation, and impairments of both general and health-related quality of life. Options for treatment include behavioral therapies, medications, and surgical treatments such as chemodenervation. Combined symptoms of OAB and benign prostatic enlargement have recently gained increased research attention. This article reviews recently published literature on epidemiology, evaluation, clinical impacts, and management of OAB, with a focus on elderly men.

摘要

膀胱过度活动症(OAB)是一种在男性和女性中都非常普遍的临床病症,且其发病率随着年龄的增长而增加。已经开发出各种不同的评估方法来测量该病症的客观和主观参数。OAB 与负面的临床结果相关,特别是在老年人中,包括抑郁、社交孤立以及一般和与健康相关的生活质量受损。治疗选择包括行为疗法、药物治疗和手术治疗,如化学神经切断术。OAB 和良性前列腺增生的综合症状最近引起了更多的研究关注。本文综述了最近发表的关于 OAB 的流行病学、评估、临床影响和管理的文献,重点关注老年男性。

相似文献

1
Overactive bladder in elderly men: epidemiology, evaluation, clinical effects, and management.老年男性膀胱过度活动症:流行病学、评估、临床影响和管理。
Curr Urol Rep. 2013 Oct;14(5):418-25. doi: 10.1007/s11934-013-0367-0.
2
Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study.美国老年人中膀胱过度活动症的流行情况及其对健康相关生活质量的影响:下尿路症状研究的流行病学结果。
J Am Geriatr Soc. 2011 Aug;59(8):1465-70. doi: 10.1111/j.1532-5415.2011.03492.x. Epub 2011 Jun 30.
3
Gender differences in overactive bladder.膀胱过度活动症的性别差异。
Can J Urol. 2016 Feb;23(Suppl 1):2-9.
4
[Prevalence and initial management of overactive bladder in France: A cross-sectional study].
Prog Urol. 2016 Jun;26(7):415-24. doi: 10.1016/j.purol.2016.04.002. Epub 2016 Apr 20.
5
Management of OAB in those over age 65.65 岁以上患者的 OAB 管理。
Curr Urol Rep. 2013 Oct;14(5):379-85. doi: 10.1007/s11934-013-0338-5.
6
The impact of overactive bladder on mental health, work productivity and health-related quality of life in the UK and Sweden: results from EpiLUTS.在英国和瑞典,过度膀胱活动症对精神健康、工作生产力和健康相关生活质量的影响:EpiLUTS 的结果。
BJU Int. 2011 Nov;108(9):1459-71. doi: 10.1111/j.1464-410X.2010.10013.x. Epub 2011 Mar 3.
7
A Narrative Review of Patient-reported Outcomes in Overactive Bladder: What is the Way of the Future?一篇关于膀胱过度活动症患者报告结局的叙述性综述:未来之路在何方?
Eur Urol. 2016 Nov;70(5):799-805. doi: 10.1016/j.eururo.2016.04.033. Epub 2016 May 6.
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Place of overactive bladder in male lower urinary tract symptoms.男性下尿路症状中膀胱过度活动症的地位。
World J Urol. 2009 Dec;27(6):723-8. doi: 10.1007/s00345-009-0470-5.
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Pharmacotherapy of overactive bladder: epidemiology and pathophysiology of overactive bladder.膀胱过度活动症的药物治疗:膀胱过度活动症的流行病学和病理生理学。
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Patterns of medical management of overactive bladder (OAB) and benign prostatic hyperplasia (BPH) in the United States.美国过度膀胱活动症(OAB)和良性前列腺增生(BPH)的医疗管理模式。
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引用本文的文献

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Translational Research and Functional Changes in Voiding Function in Older Adults.老年人排尿功能的转化研究与功能变化
Clin Geriatr Med. 2015 Nov;31(4):535-48. doi: 10.1016/j.cger.2015.06.001. Epub 2015 Jul 23.
2
The efficacy of different doses of solifenacin in elderly patients after treating a urinary tract infection.不同剂量索利那新治疗老年患者尿路感染后的疗效
Arab J Urol. 2015 Sep;13(3):203-8. doi: 10.1016/j.aju.2015.07.003. Epub 2015 Aug 5.
3
Randomized controlled trial of cyclic and continuous therapy with trospium and solifenacin combination for severe overactive bladder in elderly patients with regard to patient compliance.

本文引用的文献

1
A population-based survey of lower urinary tract symptoms (LUTS) and symptom-specific bother: results from the Brazilian LUTS epidemiology study (BLUES).基于人群的下尿路症状(LUTS)及症状特异性困扰调查:巴西 LUTS 流行病学研究(BLUES)结果。
World J Urol. 2013 Dec;31(6):1451-8. doi: 10.1007/s00345-013-1057-8. Epub 2013 Mar 21.
2
Defining and managing overactive bladder: disagreement among the experts.定义和管理过度活跃膀胱:专家意见分歧。
Urology. 2013 Feb;81(2):257-62. doi: 10.1016/j.urology.2012.09.028.
3
Increased risk of large post-void residual urine and decreased long-term success rate after intravesical onabotulinumtoxinA injection for refractory idiopathic detrusor overactivity.
曲司氯铵与索利那新联合治疗老年重度膀胱过度活动症患者的随机对照试验:患者依从性方面。
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4
Effectiveness of combined high-dosed trospium and solifenacin depending on severity of OAB symptoms in elderly men and women under cyclic therapy.在老年男性和女性的周期性治疗中,根据膀胱过度活动症(OAB)症状的严重程度,联合使用高剂量曲司氯铵和索利那新的有效性。
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膀胱内注射奥昔布宁毒素 A 治疗难治性特发性逼尿肌过度活动后,发生大残余尿和长期成功率降低的风险增加。
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Pharmacokinetic properties of mirabegron, a β3-adrenoceptor agonist: results from two phase I, randomized, multiple-dose studies in healthy young and elderly men and women.米拉贝隆的药代动力学特性:来自两项在健康年轻和老年男女中进行的 I 期、随机、多剂量研究的结果。β3-肾上腺素能受体激动剂。
Clin Ther. 2012 Oct;34(10):2144-60. doi: 10.1016/j.clinthera.2012.09.010.
5
Association of symptoms with urodynamic findings in men with overactive bladder syndrome.男性膀胱过度活动症患者症状与尿动力学检查结果的相关性。
BJU Int. 2012 Dec;110(11 Pt C):E891-5. doi: 10.1111/j.1464-410X.2012.11467.x. Epub 2012 Aug 29.
6
The prevalence of lower urinary tract symptoms (LUTS) and overactive bladder (OAB) by racial/ethnic group and age: results from OAB-POLL.按种族/族群和年龄划分的下尿路症状(LUTS)和膀胱过度活动症(OAB)的流行率:OAB-POLL 的结果。
Neurourol Urodyn. 2013 Mar;32(3):230-7. doi: 10.1002/nau.22295. Epub 2012 Jul 27.
7
Solifenacin plus tamsulosin combination treatment in men with lower urinary tract symptoms and bladder outlet obstruction: a randomized controlled trial.索利那新联合坦索罗辛治疗下尿路症状和膀胱出口梗阻的男性患者:一项随机对照试验。
Eur Urol. 2013 Jan;63(1):158-65. doi: 10.1016/j.eururo.2012.07.003. Epub 2012 Jul 17.
8
Effect of bothersome overactive bladder symptoms on health-related quality of life, anxiety, depression, and treatment seeking in the United States: results from EpiLUTS.美国中令人困扰的膀胱过度活动症症状对健康相关生活质量、焦虑、抑郁和治疗寻求的影响:EpiLUTS 的结果。
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Patient-reported goal achievement after antimuscarinic treatment in patients with overactive bladder symptoms.患者报告的抗毒蕈碱药物治疗逼尿症症状患者的目标达成情况。
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10
Association between metabolic syndrome and male overactive bladder in a Japanese population based on three different sets of criteria for metabolic syndrome and the Overactive Bladder Symptom Score.基于三种不同的代谢综合征标准和膀胱过度活动症症状评分,在日本人群中,代谢综合征与男性膀胱过度活动症之间的关系。
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