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输血相关急性肺损伤:一种危险且诊断不足的非心源性肺水肿。

Transfusion-related acute lung injury: a dangerous and underdiagnosed noncardiogenic pulmonary edema.

出版信息

Cardiol J. 2013;20(4):337-44. doi: 10.5603/CJ.2013.0091.

DOI:10.5603/CJ.2013.0091
PMID:23913451
Abstract

Transfusion-related acute lung injury (TRALI) is one of the leading causes of death associated with transfusion of blood and blood components. The understanding of the etiology and pathophysiology of this syndrome has much improved during the last decades, nevertheless numerous issues are still unresolved and symptomatic treatment remains the cornerstone of medical management. Consequently more attention is directed at primary as well as secondary prevention. The awareness of the problem within the medical society is still unsatisfactory which results in a high number of unrecognized cases or of inaccurate diagnoses one of which is cardiogenic pulmonary edema. The aim of this review is to make the TRALI syndrome more familiar to clinicians and to emphasize how significant proper medical management is both for the patients presenting TRALI symptoms as well as for future recipients of blood components.

摘要

输血相关急性肺损伤(TRALI)是输血相关死亡的主要原因之一。尽管过去几十年对该综合征的病因学和病理生理学有了更深入的了解,但仍有许多问题尚未解决,对症治疗仍然是医学管理的基石。因此,更多的注意力集中在一级和二级预防上。医学界对该问题的认识仍然不尽如人意,导致大量未被识别的病例或不准确的诊断,其中之一是心源性肺水肿。本综述的目的是使 TRALI 综合征更被临床医生所熟悉,并强调正确的医疗管理对出现 TRALI 症状的患者以及未来的血液成分接受者都非常重要。

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