Alsara Osama, Rayamajhi Supratik, Ghanem Firas, Skaf Elias, Abela George S
Department of Internal Medicine, Division of General Internal Medicine, Michigan State University, East Lansing, Michigan 48824, USA.
Tex Heart Inst J. 2013;40(3):339-42.
Soft-tissue sarcoma is the most prevalent primary malignant cardiac tumor. This sarcoma usually presents with cardiac manifestations secondary to local obstruction or arrhythmias; very rarely does it present with initial symptoms of distant metastasis. We discuss the unusual case of an 18-year-old man who emergently presented with acute-on-chronic back pain. Imaging revealed a lesion on the 12th thoracic vertebra and a large mass arising from the left atrium. The cardiac mass was resected, and immunohistochemical analysis revealed it to be a pleomorphic sarcoma that had metastasized to the spine. The patient died 2 years later of diffuse metastases. In addition to the patient's case, we discuss the nature and treatment of cardiac sarcoma.
软组织肉瘤是最常见的原发性心脏恶性肿瘤。这种肉瘤通常表现为继发于局部梗阻或心律失常的心脏症状；极少以远处转移的初始症状出现。我们讨论了一例不寻常的病例，一名18岁男性因慢性背痛急性发作而紧急就诊。影像学检查显示第12胸椎有一个病变，左心房有一个大肿块。切除了心脏肿块，免疫组化分析显示为多形性肉瘤，已转移至脊柱。患者两年后死于弥漫性转移。除了该患者的病例外，我们还讨论了心脏肉瘤的性质和治疗。
