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一名18岁男性原发性心脏多形性肉瘤表现为背痛。

Primary cardiac pleomorphic sarcoma presenting as back pain in an 18-year-old man.

作者信息

Alsara Osama, Rayamajhi Supratik, Ghanem Firas, Skaf Elias, Abela George S

机构信息

Department of Internal Medicine, Division of General Internal Medicine, Michigan State University, East Lansing, Michigan 48824, USA.

出版信息

Tex Heart Inst J. 2013;40(3):339-42.

Abstract

Soft-tissue sarcoma is the most prevalent primary malignant cardiac tumor. This sarcoma usually presents with cardiac manifestations secondary to local obstruction or arrhythmias; very rarely does it present with initial symptoms of distant metastasis. We discuss the unusual case of an 18-year-old man who emergently presented with acute-on-chronic back pain. Imaging revealed a lesion on the 12th thoracic vertebra and a large mass arising from the left atrium. The cardiac mass was resected, and immunohistochemical analysis revealed it to be a pleomorphic sarcoma that had metastasized to the spine. The patient died 2 years later of diffuse metastases. In addition to the patient's case, we discuss the nature and treatment of cardiac sarcoma.

摘要

软组织肉瘤是最常见的原发性心脏恶性肿瘤。这种肉瘤通常表现为继发于局部梗阻或心律失常的心脏症状;极少以远处转移的初始症状出现。我们讨论了一例不寻常的病例,一名18岁男性因慢性背痛急性发作而紧急就诊。影像学检查显示第12胸椎有一个病变,左心房有一个大肿块。切除了心脏肿块,免疫组化分析显示为多形性肉瘤,已转移至脊柱。患者两年后死于弥漫性转移。除了该患者的病例外,我们还讨论了心脏肉瘤的性质和治疗。

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本文引用的文献

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Am J Surg. 2003 Dec;186(6):641-7; discussion 647. doi: 10.1016/j.amjsurg.2003.08.004.
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