Xu Zhi-rong, Wang Zhe-ming, Xu Ming-zhu, He Hua-fei
Environmental Science Research and Design Institute of Zhejiang Province, Hangzhou 310007, China.
Huan Jing Ke Xue. 2013 May;34(5):1864-70.
In the present study, the main source and characteristics of volatile organic compounds (VOCs) released from pharmaceutical industry in Zhejiang Province were analyzed quantitatively and qualitatively. Based on these results, the internationally recognized evaluation model for health risk assessment and ozone formation potentials (OFP) was adopted to preliminarily assess the environmental impact and health risk of those VOCs. The results showed that the OFP of VOCs was in the range of 16.1-79, 2 mL x m(-3), based on the maximum incremental reactivity. The principal contribution of VOCs was from nine kinds of substances including ethyl acetate, acetone, toluene and xylene, etc. Moreover, the health risk of VOCs was mainly generated from benzene, ethylene oxide, dichloromethane and formaldehyde owing to their carcinogenicity, which could account for more than 69% in the value of non-carcinogenic risk and 100% in the cancer risk. Additionally, according to the comparison of these assessments, the environmental hazards and health risk produced by VOCs could not be neglected during the development of VOCs emissions standards, especially in the screening of the control factors for the standards.
在本研究中，对浙江省制药行业排放的挥发性有机化合物（VOCs）的主要来源和特征进行了定量和定性分析。基于这些结果，采用国际认可的健康风险评估和臭氧生成潜势（OFP）评估模型，对这些VOCs的环境影响和健康风险进行了初步评估。结果表明，基于最大增量反应活性，VOCs的OFP在16.1 - 79.2 mL x m(-3)范围内。VOCs的主要贡献来自乙酸乙酯、丙酮、甲苯和二甲苯等九种物质。此外，由于苯、环氧乙烷、二氯甲烷和甲醛具有致癌性，它们是VOCs健康风险的主要来源，在非致癌风险值中占比超过69%，在致癌风险中占比100%。此外，根据这些评估结果的比较，在制定VOCs排放标准时，尤其是在筛选标准的控制因子时，VOCs产生的环境危害和健康风险不容忽视。
