过敏反应后豚鼠肺脏肺泡内衬层的表面活性

The surface activity of the alveolar lining layer of guinea-pig lung following anaphylaxis.

作者信息

Goadby P

出版信息

J Pharm Pharmacol. 1975 Jul;27(7):479-83. doi: 10.1111/j.2042-7158.1975.tb09488.x.

DOI:10.1111/j.2042-7158.1975.tb09488.x

Abstract

The surface activity and lipid composition of alveolar extracts of guinea-pig lung following anaphylaxis have been studied. The extracts showed a reduced ability to lower surface tension on compression of the surface film which was maximal 30 min after challenge. No significant changes in the lipid content were found but there was a marked increase in the soluble solids 10 min after anaphylactic shock. The significance of these findings is discussed.

摘要

对豚鼠肺过敏性反应后肺泡提取物的表面活性和脂质成分进行了研究。提取物在表面膜压缩时降低表面张力的能力下降，这种情况在激发后30分钟时最为明显。脂质含量未发现显著变化，但过敏性休克10分钟后可溶性固体有明显增加。对这些发现的意义进行了讨论。