Screening Programs, CancerCare Manitoba, Winnipeg Manitoba, Canada.
J Womens Health (Larchmt). 2013 Aug;22(8):687-93. doi: 10.1089/jwh.2012.4203.
The objective of this study was to evaluate the effectiveness of an invitation letter on cervical screening participation among unscreened women 30 to 69 years of age.
A cluster randomized trial design was used in which unscreened women (n=31,452) were randomized by the forward sortation area (FSA) of their postal code to an intervention group that was sent an invitation letter (n=17,068) or a group that was not sent an invitation letter (n=14,384).
Six months after the letters were mailed, 1,010 women in the intervention group (5.92%) and 441 women in the control group (3.06%) had a Pap test. After adjusting for variables that have previously shown to influence screening participation, women who were sent an invitation letter were significantly more likely to have had a Pap test in the next 6 months compared with women who were not sent an invitation letter (odds ratio [OR]=2.60, 95% confidence interval [CI] 2.09-3.35, p<0.001). Overall, the effectiveness of the invitation letter improved with increasing age (p=0.02).
Sending invitation letters increased cervical screening participation but because the overall effect was small, additional strategies that remove barriers to screening for unscreened women are also necessary.
本研究旨在评估针对 30 至 69 岁未接受筛查的女性，通过邀请信提高子宫颈筛查参与度的效果。
采用整群随机试验设计，将未接受筛查的女性（n=31452）按邮政编码的前向排序区（FSA）随机分为干预组（n=17068）和对照组（n=14384）。干预组收到邀请信，对照组未收到邀请信。
在信件寄出后的 6 个月，干预组有 1010 名女性（5.92%）和对照组有 441 名女性（3.06%）接受了巴氏涂片检查。在调整了先前显示会影响筛查参与的变量后，与未收到邀请信的女性相比，收到邀请信的女性在接下来的 6 个月内接受巴氏涂片检查的可能性显著更高（比值比 [OR]=2.60，95%置信区间 [CI] 2.09-3.35，p<0.001）。总体而言，邀请信的效果随着年龄的增加而提高（p=0.02）。
发送邀请信可提高子宫颈筛查参与度，但由于总体效果较小，还需要采取其他策略来消除未接受筛查女性的筛查障碍。
