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预测胎盘早剥胎儿酸中毒。

Prediction of fetal acidemia in placental abruption.

机构信息

Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Kawada-cho, 8-1, Shinjuku-ku, Tokyo 162-8666, Japan.

出版信息

BMC Pregnancy Childbirth. 2013 Aug 1;13:156. doi: 10.1186/1471-2393-13-156.

Abstract

BACKGROUND

To determine the major predictive factors for fetal acidemia in placental abruption.

METHODS

A retrospective review of pregnancies with placental abruption was performed using a logistic regression model. Fetal acidemia was defined as a pH of less than 7.0 in umbilical artery. The severe abruption score, which was derived from a linear discriminant function, was calculated to determine the probability of fetal acidemia.

RESULTS

Fetal acidemia was seen in 43 survivors (43/222, 19%). A logistic regression model showed bradycardia (OR (odds ratio) 50.34, 95% CI 11.07-228.93), and late decelerations (OR 15.13, 3.05-74.97), but not abnormal ultrasonographic findings were to be associated with the occurrence of fetal acidemia. The severe abruption score was calculated for the occurrence of fetal acidemia, using 6 items including vaginal bleeding, gestational age, abdominal pain, abnormal ultrasonographic finding, late decelerations, and bradycardia.

CONCLUSIONS

An abnormal FHR pattern, especially bradycardia is the most significant risk factor in placental abruption predicting fetal acidemia, regardless of the presence of abnormal ultrasonographic findings or gestational age.

摘要

背景

确定胎盘早剥胎儿酸中毒的主要预测因素。

方法

使用逻辑回归模型对胎盘早剥的妊娠进行回顾性分析。胎儿酸中毒定义为脐动脉 pH 值小于 7.0。计算严重胎盘早剥评分,这是一种源自线性判别函数的概率,用于确定胎儿酸中毒的可能性。

结果

43 名幸存者(222 名中的 43 名,19%)出现胎儿酸中毒。逻辑回归模型显示心动过缓(OR 50.34,95%CI 11.07-228.93)和晚期减速(OR 15.13,3.05-74.97)与胎儿酸中毒的发生有关,而异常的超声发现与胎儿酸中毒的发生无关。使用包括阴道出血、胎龄、腹痛、超声异常、晚期减速和心动过缓在内的 6 项指标计算严重胎盘早剥评分,以预测胎儿酸中毒的发生。

结论

异常的胎心监护模式,尤其是心动过缓是预测胎盘早剥胎儿酸中毒的最重要危险因素,无论是否存在超声异常或胎龄。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee31/3735466/5ed2d2e66f57/1471-2393-13-156-1.jpg

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