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对未经活检证实癌症而转诊行手术的息肉患者进行重复结肠镜检查的结果。

Outcomes of repeat colonoscopy in patients with polyps referred for surgery without biopsy-proven cancer.

机构信息

Department of Gastroenterology, Stanford University School of Medicine, Stanford, California, USA; VA Palo Alto Health Care System, Palo Alto, California, USA.

Department of Gastroenterology, Stanford University School of Medicine, Stanford, California, USA.

出版信息

Gastrointest Endosc. 2014 Jan;79(1):101-7. doi: 10.1016/j.gie.2013.06.034. Epub 2013 Jul 31.

Abstract

BACKGROUND

Despite advances in endoscopic treatment, many colonic adenomas are still referred for surgical resection. There is a paucity of data on the suitability of these lesions for endoscopic treatment.

OBJECTIVE

To analyze the results of routine repeat colonoscopy in patients referred for surgical resection of colon polyps without biopsy-proven cancer.

DESIGN

Retrospective review.

SETTING

University hospital.

PATIENTS

Patients referred to a colorectal surgeon for surgical resection of a polyp without biopsy-proven cancer.

INTERVENTIONS

Repeat colonoscopy.

MAIN OUTCOME MEASUREMENTS

The rate of successful endoscopic treatment.

RESULTS

There were 38 lesions in 36 patients; 71% of the lesions were noncancerous and were successfully treated endoscopically. In 26% of the lesions, previous removal was attempted by the referring physician but was unsuccessful. The adenoma recurrence rate was 50%, but all recurrences were treated endoscopically and none were cancerous. Two patients were admitted for overnight observation. There were no major adverse events.

LIMITATIONS

Single center, retrospective.

CONCLUSIONS

In the absence of biopsy-proven invasive cancer, it is appropriate to reevaluate patients referred for surgical resection by repeat colonoscopy at an expert center.

摘要

背景

尽管内镜治疗取得了进展,但仍有许多结肠腺瘤需要手术切除。对于这些病变是否适合内镜治疗,相关数据很少。

目的

分析因无活检证实的癌症而被转介行外科切除术的结肠息肉患者常规重复结肠镜检查的结果。

设计

回顾性研究。

地点

大学医院。

患者

因无活检证实的癌症而被转介至结直肠外科医生处行外科切除术的患者。

干预措施

重复结肠镜检查。

主要观察指标

成功进行内镜治疗的比例。

结果

36 例患者中有 38 个病灶;71%的病灶是非癌症性的,并成功地进行了内镜治疗。在 26%的病灶中,之前的内镜切除是由转介医生尝试的,但未成功。腺瘤的复发率为 50%,但所有复发均经内镜治疗,且均无癌症。有 2 名患者接受了过夜观察。无重大不良事件。

局限性

单中心,回顾性。

结论

在无活检证实的浸润性癌症的情况下,在专家中心通过重复结肠镜检查对因手术切除而被转介的患者进行重新评估是合适的。

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