Anaesthesia and Operative Services, Kuopio University Hospital, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Int J Obstet Anesth. 2013 Nov;22(4):303-9. doi: 10.1016/j.ijoa.2013.04.012. Epub 2013 Jul 31.
Postdural puncture headache is common in parturients following lumbar puncture. If headache is severe and persistent, an epidural blood patch is recommended. In this paper we reviewed the efficacy of epidural blood patches over a 13-year period at two hospitals in Finland with a particular emphasis on its timing.
The hospitals' databases were searched to identify parturients who underwent an epidural blood patch from March 1998 to June 2011. Parturients' records were reviewed to establish the characteristics and associated symptoms of headache and the effectiveness of the epidural blood patch.
A total of 129 parturients received 151 epidural blood patches. These followed spinal (n = 49), epidural (n = 47) or combined spinal-epidural blocks (n = 33). The success rate of the first procedure was 89%, with permanent relief in 76%. The first procedure provided permanent relief of postdural puncture headache for 86% of 78 patients having the procedure after 48 h, compared to 65% of 37 patients when it was performed between 24 and 48 h, and 50% of 14 patients with the procedure within the first 24 h after dural puncture (P = 0.003). A second procedure was performed for 22 parturients due to incomplete relief (n = 5) or recurrent symptoms (n = 17); all had complete resolution of symptoms.
Epidural blood patch performed later than 48 h following lumbar puncture or accidental dural puncture is effective in parturients with postdural puncture symptoms. The recurrence rate of symptoms after an initially successful epidural blood patch is high, and therefore patients should be provided with counselling and contact information.
产妇行腰椎穿刺后常发生硬脊膜后穿刺头痛。如果头痛严重且持续,建议行硬膜外血贴治疗。本文主要关注硬膜外血贴的时机,回顾了芬兰两家医院 13 年来的治疗效果。
检索医院数据库,确定 1998 年 3 月至 2011 年 6 月期间行硬膜外血贴治疗的产妇。回顾产妇病历,明确头痛特征及相关症状,评估硬膜外血贴的治疗效果。
共 129 例产妇行 151 次硬膜外血贴治疗,其中脊髓穿刺(n=49)、硬膜外穿刺(n=47)或腰硬联合穿刺(n=33)后各 49、47、33 例。首次治疗成功率为 89%,永久性缓解率为 76%。48 小时后行硬膜外血贴的 78 例患者中,86%首次治疗即刻缓解头痛,24~48 小时行硬膜外血贴的 37 例患者中,65%首次治疗即刻缓解头痛,穿刺后 24 小时内行硬膜外血贴的 14 例患者中,50%首次治疗即刻缓解头痛(P=0.003)。22 例患者因治疗效果不完全(n=5)或症状复发(n=17)行第 2 次硬膜外血贴治疗,所有患者症状均完全缓解。
穿刺后或意外穿刺后 48 小时后行硬膜外血贴治疗对有硬脊膜后穿刺头痛症状的产妇有效。首次硬膜外血贴治疗成功后症状复发率较高,因此应为患者提供咨询和联系方式。