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因 Exner 区梗死导致的失写症。

Agraphia caused by an infarction in Exner's area.

机构信息

Universitätsklinik Köln, Klinik und Poliklinik für Neurologie, Kerpener Strasse 62, Köln 50924, Germany.

Universitätsklinik Köln, Klinik und Poliklinik für Neurologie, Kerpener Strasse 62, Köln 50924, Germany.

出版信息

J Clin Neurosci. 2014 Jan;21(1):172-3. doi: 10.1016/j.jocn.2013.01.014. Epub 2013 Jul 31.

DOI:10.1016/j.jocn.2013.01.014
PMID:23916761
Abstract

Sigmund Exner postulated in 1881 that lesions of the base of the medial frontal gyrus could specifically produce writing impairments and attributed the writing centre to this area. We report two patients who suffered from strokes in this area. These patients suffered from writing disturbances comprising both omitted words within a sentence or badly written words, as well as aphasia. These patients, in line with prior reports, illustrate the crucial role of the Exner area at the base of the medial frontal gyrus for the cerebral writing network; we suggest that this region plays an important role for phoneme-grapheme conversions.

摘要

西格蒙德·埃克纳(Sigmund Exner)于 1881 年提出,内侧额上回底部的病变可能会特异性地导致书写障碍,并将书写中心归因于这一区域。我们报告了两名在该区域患有中风的患者。这些患者患有书写障碍,包括句子中遗漏的单词或书写不佳的单词,以及失语症。这些患者与之前的报告一致,说明了内侧额上回底部埃克纳区域在大脑书写网络中的关键作用;我们认为该区域对于音位-字形转换起着重要作用。

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