Ergül Yakup, Kıplapınar Neslihan, Akdeniz Celal, Tuzcu Volkan
Department of Pediatric Cardiology, Mehmet Akif Ersoy Cardiovascular Training and Research Hospital, İstanbul, Turkey.
Turk Kardiyol Dern Ars. 2013 Jul;41(5):436-9. doi: 10.5543/tkda.2013.96155.
We present a six-year-old boy with a history of recurrent syncope whose physical examination and family history were inconclusive. Laboratory findings, 12-lead ECG, chest radiography, Holter monitoring, event recorder monitoring, echocardiography, coronary computed tomography (CT) angiography, Brugada challenge test (ajmaline), cranial magnetic resonance imaging, and awake/sleep electroencephalogram were all unremarkable. Since syncope was exercise-induced, an electrophysiology study was also performed, but revealed no inducible ventricular arrhythmias. Implantable loop recorder (ILR) was implanted. Three weeks later, bidirectional ventricular tachycardia was found in ILR record during presyncope that was related to exercise. The patient, with the diagnosis of catecholaminergic polymorphic ventricular tachycardia, was started on high-dose beta-blocker therapy. Due to the recurrence of syncopes despite the presence of beta-blockers, an implantable cardioverter defibrillator was implanted.
我们报告一名有反复晕厥病史的6岁男孩,其体格检查和家族史均无定论。实验室检查结果、12导联心电图、胸部X线、动态心电图监测、事件记录仪监测、超声心动图、冠状动脉计算机断层扫描(CT)血管造影、Brugada激发试验(阿义马林)、头颅磁共振成像以及清醒/睡眠脑电图均无异常。由于晕厥是运动诱发的,因此还进行了电生理研究,但未诱发出室性心律失常。植入了植入式环路记录仪(ILR)。三周后,在晕厥前的ILR记录中发现了与运动相关的双向室性心动过速。该患者被诊断为儿茶酚胺能多形性室性心动过速,开始接受高剂量β受体阻滞剂治疗。尽管使用了β受体阻滞剂,晕厥仍有复发,遂植入了植入式心脏复律除颤器。