Mohammadi Mahshid, Sharp Kendra V
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J Fluids Eng. 2013 Feb;135(2):212021-2120210. doi: 10.1115/1.4023450. Epub 2013 Mar 19.
Experimental studies employing advanced measurement techniques have played an important role in the advancement of two-phase microfluidic systems. In particular, flow visualization is very helpful in understanding the physics of two-phase phenomenon in microdevices. The objective of this article is to provide a brief but inclusive review of the available methods for studying bubble dynamics in microchannels and to introduce prior studies, which developed these techniques or utilized them for a particular microchannel application. The majority of experimental techniques used for characterizing two-phase flow in microchannels employs high-speed imaging and requires direct optical access to the flow. Such methods include conventional brightfield microscopy, fluorescent microscopy, confocal scanning laser microscopy, and micro particle image velocimetry (micro-PIV). The application of these methods, as well as magnetic resonance imaging (MRI) and some novel techniques employing nonintrusive sensors, to multiphase microfluidic systems is presented in this review.
采用先进测量技术的实验研究在两相微流体系统的发展中发挥了重要作用。特别是，流动可视化对于理解微器件中两相现象的物理过程非常有帮助。本文的目的是对研究微通道中气泡动力学的现有方法进行简要但全面的综述，并介绍先前开发这些技术或将其用于特定微通道应用的研究。用于表征微通道中两相流的大多数实验技术都采用高速成像，并且需要对流动进行直接光学观察。这些方法包括传统的明场显微镜、荧光显微镜、共聚焦扫描激光显微镜和微粒子图像测速技术（micro-PIV）。本综述介绍了这些方法以及磁共振成像（MRI）和一些采用非侵入式传感器的新技术在多相微流体系统中的应用。
