Tanaka Yoji, Ohno Kikuo
Neurosurgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University(TMDU), Tokyo, Japan.
J Med Dent Sci. 2013 Jun 1;60(2):55-61.
Chronic subdural hematoma (CSDH) is prevalent among elderly populations worldwide, and its mysterious pathogenesis has been discussed in the literature for decades. The issues remaining to be solved in regard to CSDH include the initiating events; the bleeding into the subdural space and the formation of the outer and inner membranes, its development; increase and liquefaction of hematoma, the optimal treatments, and the natural history. The pathophysiology is becoming more clear due to recent findings from computed tomography studies and human models of CSDH. In this work, we review previous studies on CSDH and present a new integrated concept about the development of this common condition after head injuries.
慢性硬膜下血肿(CSDH)在全球老年人群中普遍存在,其神秘的发病机制在文献中已讨论了数十年。关于CSDH仍有待解决的问题包括起始事件;血液进入硬膜下间隙以及外层和内层膜的形成、其发展过程;血肿的增大和液化、最佳治疗方法以及自然病程。由于计算机断层扫描研究和CSDH人体模型的最新发现,其病理生理学正变得更加清晰。在这项工作中,我们回顾了以往关于CSDH的研究,并提出了一种关于头部受伤后这种常见病症发展的新综合概念。