Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
J Gastrointest Surg. 2013 Oct;17(10):1826-31. doi: 10.1007/s11605-013-2291-5. Epub 2013 Aug 6.
The pancreas can serve as the destination for metastatic spread of malignancies from multiple organ sites. Breast cancer metastases to the pancreas are part of this spectrum and surgeons evaluate such patients as part of their practice. Uniform clinical guidelines for these cases do not exist and care is primarily driven by the personal experience of the treating surgeon.
We present two patients with breast cancer metastases to their pancreas and review their workup and clinical management in light of our experience and the existing published literature. We propose that metastatic disease to the pancreas has to remain in the differential diagnosis for any patient with a new pancreatic mass and prior cancer history. Surgical resection is a viable treatment option for patients with isolated metastatic disease to the pancreas if the underlying biology of the metastatic tumor is favorable.
胰腺可能是来自多个器官部位的恶性肿瘤转移的靶器官。乳腺癌转移至胰腺属于这种情况，外科医生在其工作中评估此类患者。目前针对此类病例尚无统一的临床指南，治疗主要取决于手术医生的个人经验。
我们报告了 2 例乳腺癌转移至胰腺的患者，并根据我们的经验和现有文献回顾了他们的检查和临床管理。我们提出，对于任何有新发胰腺肿块和既往癌症病史的患者，胰腺转移瘤仍需纳入鉴别诊断。如果转移瘤的生物学特性有利，对于孤立性胰腺转移瘤的患者，手术切除是一种可行的治疗选择。
