Baskent University School of Medicine, Pulmonary Diseases Department, Ankara, Turkey.
Pulmonary & Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
Chest. 2013 Aug;144(2):651-660. doi: 10.1378/chest.13-0080.
Aspiration of a medication in the airways in any form produces a variety of adverse effects, both local and systemic. Furthermore, specific reaction of the airways to each type of pill strongly affects the outcome. It is crucial for pulmonologists and emergency medicine specialists to acknowledge this clinical entity. In addition, airways have been increasingly used to deliver medications such as insulin and prostacycline. These aerosolized medications can also cause local as well as systemic side effects. We review the local and systemic reactions of these "pills" accessing the airways either by incidental aspiration or iatrogenic administration. We address clinical presentation, mechanism of injury, diagnosis, and management of complications of these pills in the air passages.
任何形式的药物吸入气道都会产生各种局部和全身的不良反应。此外，气道对每种药丸类型的特定反应强烈影响治疗结果。这对于肺病学家和急诊医学专家来说至关重要。此外，气道越来越多地被用于输送胰岛素和前列环素等药物。这些气溶胶药物也会引起局部和全身副作用。我们通过偶然吸入或医源性给药来评估这些“药丸”对气道的局部和全身反应。我们探讨了这些气道内“药丸”的临床表现、损伤机制、诊断和并发症处理。
