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银屑病中的指甲点状凹陷及其与不同变量的关系。

Finger nail pitting in psoriasis and its relation with different variables.

作者信息

Singh Satyendra Kumar

机构信息

Departments of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

Indian J Dermatol. 2013 Jul;58(4):310-2. doi: 10.4103/0019-5154.113955.

DOI:10.4103/0019-5154.113955
PMID:23919005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3726881/
Abstract

Incidence of pitting, vary considerably in different types of psoriasis. In clinical practice, toe nail examination is inconvenient. There are inadequate studies which show relation of nail pitting with duration and severity of the disease. The objective was to examine the incidence of finger nail pitting in all types of cutaneous psoriasis and its relation with different variables. This is a clinico-epidemiological study. A careful clinical examination of finger nails was done in day time. Severity of disease was calculated by psoriasis area severity index (PASI). Statistical analysis was done using Microcomputer statistics software (MSTAT). In study group, 621 patients and in control group 350 people were taken. Finger nail pitting was present in 37% (total number was < 20 in 17%; 20-60 in 8% and > 60 in 12%) in study group. In control group, it was present in 10% (in all cases total number was < 20). In < 1 year duration group, pitting was present in 32% of cases, while in > 1 year duration group it was 40.5%. In mild psoriasis, pitting was present in 34.2%, while in severe cases it was 47.6%. Finger nail pitting is an important nail finding in psoriasis and its incidence increases with duration and severity of disease.

摘要

点状凹陷的发生率在不同类型的银屑病中差异很大。在临床实践中,检查趾甲不太方便。关于点状凹陷与疾病持续时间和严重程度之间关系的研究尚不充分。本研究的目的是调查各类皮肤银屑病中指甲点状凹陷的发生率及其与不同变量的关系。这是一项临床流行病学研究。白天对手指甲进行了仔细的临床检查。疾病严重程度通过银屑病面积严重程度指数(PASI)计算。使用微机统计软件(MSTAT)进行统计分析。研究组纳入621例患者,对照组纳入350人。研究组中37%的患者存在指甲点状凹陷(总数<20的占17%;20 - 60的占8%;>60的占12%)。对照组中,10%的人存在指甲点状凹陷(所有病例总数均<20)。病程<1年的组中,32%的病例有点状凹陷,而病程>1年的组中这一比例为40.5%。轻度银屑病患者中,34.2%有点状凹陷,而重度患者中这一比例为47.6%。指甲点状凹陷是银屑病中一项重要的指甲表现,其发生率随疾病持续时间和严重程度的增加而升高。

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