Kandaswamy Shakthisri, Akhtar Nahid, Ravindran Surya, Prabhu Smitha, Shenoi Shrutakirthi D
Department of Dermatology, Kasturba Medical College, Manipal University, Manipal, India.
Indian J Dermatol. 2013 Jul;58(4):325. doi: 10.4103/0019-5154.113944.
Vitiligo is a chronic, benign, but emotionally frustrating autoimmune disorder of depigmentation, with an incidence of 0.25-2.5% in India, the treatment of which is equally frustrating to the patient, as well as the doctor. Phototherapy is the first line treatment in many cases, which needs to be given at frequent sittings for long periods of time. As there is no satisfactory, short term treatment, many vitiligo patients, though enthusiastic in the beginning, become defaulters after a few weeks or months.
This study was conducted to assess the compliance to phototherapy (PUVA and NB-UVB), determine the reasons for non-compliance, to calculate the overall response to phototherapy and to know about the patients' perception about improvement of lesions.
All files of the patients who attended phototherapy for Vitiligo in the department for a period of 4 years from January 2007 were analyzed and the patients were contacted via mail or telephone and were made to answer questionnaire regarding their disease.
At the end of this retrospective questionnaire based study we concluded that only a quarter of the patients underwent regular phototherapy, among which the younger patients and those with widespread disease and facial lesions were more compliant. Educational status and sex had no impact on default status.
白癜风是一种慢性、良性但令人情绪沮丧的色素脱失性自身免疫性疾病，在印度的发病率为0.25%-2.5%，其治疗对患者和医生来说同样令人沮丧。光疗是许多病例的一线治疗方法，需要长时间频繁进行。由于没有令人满意的短期治疗方法，许多白癜风患者尽管一开始热情高涨，但几周或几个月后就不再坚持治疗。
本研究旨在评估光疗（补骨脂素加长波紫外线及窄谱中波紫外线）的依从性，确定不依从的原因，计算光疗的总体反应，并了解患者对皮损改善的看法。
分析了2007年1月起4年内该科室接受白癜风光疗患者的所有病历，并通过邮件或电话联系患者，让他们回答有关其疾病的问卷。
在这项基于回顾性问卷的研究结束时，我们得出结论，只有四分之一的患者接受了正规的光疗，其中年轻患者以及患有广泛疾病和面部皮损的患者更依从。教育程度和性别对不坚持治疗的情况没有影响。
