Sonavane Sunita Tarsarya, Lahoti Amrita, Jaiswar Rajnath
Department of Nuclear Medicine and PET, Bombay Hospital and Medical Research Centre, Mumbai, India.
Indian J Nucl Med. 2012 Jul;27(3):192-5. doi: 10.4103/0972-3919.112734.
A young male patient with end stage renal disease underwent renal allograft having dual arterial supply. Immediate post-operative urine output dropped, an urgent Technetium-99m-mercaptoacetyltriglycine ((99m)Tc-MAG3) renogram revealed non-visualized upper-half and the preserved perfusion and parenchymal function of the small transplant kidney. Patient was re-explored and re-anastomosis was performed. A renogram at 24h post re-anastomosis revealed increase in the size of renal allograft, with preserved perfusion to the upper-half of transplant. Transplant kidney biopsy of the Upper-half showed acute tubular necrosis. 99mTc-MAG3renogram at 10 days post re-vascularization remains unchanged with persistent improvement at 2 months follow-up. We conclude that early recognition of renal functional loss allows early management and the high probability of salvaging the renal function.
一名患有终末期肾病的年轻男性患者接受了具有双动脉供应的同种异体肾移植。术后即刻尿量减少,紧急进行的锝-99m-巯基乙酰三甘氨酸((99m)Tc-MAG3)肾图显示移植肾的上半部分未显影,而小移植肾的灌注和实质功能得以保留。患者接受了再次探查并进行了重新吻合术。重新吻合术后24小时的肾图显示同种异体肾的大小增加,移植肾上半部分的灌注得以保留。上半部分移植肾活检显示急性肾小管坏死。血管重建术后10天的99mTc-MAG3肾图保持不变,在2个月的随访中持续改善。我们得出结论,早期识别肾功能丧失可实现早期管理,并极有可能挽救肾功能。