Sayman H B, Sönmezoglu K, Ayaz M, Kahraman N, Kapicioglu T, Urgancioglu I
Department of Nuclear Medicine, Istanbul University, Cerrahpasa Medical Faculty, Turkey.
J Nucl Biol Med (1991). 1993 Sep;37(3):115-8.
A variety of techniques have been employed to assess renal function and its evolution after transplant surgery. Since initial perfusion studies are easy to perform, one may be tempted to rely on 99mTc-diethylenetriaminepentaacetic acid (DTPA) scanning alone. Some discrepancies have been observed between perfusion studies and clinical outcome of the renal transplant patients however. We therefore decided to evaluate both 99mTc-DTPA and 131I-hippuran renal scanning in 28 renal transplant patients. Sixty 99mTc-DTPA perfusion and 131I hippuran scintigraphies were performed using a same-day protocol. The examinations were repeated in 14 patients at weekly or monthly intervals to monitor the clinical trend of these patients. The results of this study indicate that, for early detection of the kidney problems, 131I-hippuran scintigraphy was superior to 99mTc-DTPA perfusion scans, but for the proper clinical management of renal transplant patients, both procedures should be utilized.
人们运用了多种技术来评估移植手术后的肾功能及其变化情况。由于初始灌注研究易于实施,有人可能会倾向于仅依靠99m锝-二乙三胺五乙酸(DTPA)扫描。然而,在肾移植患者的灌注研究与临床结果之间已观察到一些差异。因此,我们决定对28例肾移植患者进行99mTc-DTPA和131碘-马尿酸肾扫描评估。按照当日方案进行了60次99mTc-DTPA灌注和131碘-马尿酸闪烁扫描。14例患者每隔一周或一个月重复进行检查,以监测这些患者的临床动态。本研究结果表明,对于早期发现肾脏问题,131碘-马尿酸闪烁扫描优于99mTc-DTPA灌注扫描,但对于肾移植患者的合理临床管理,两种检查都应采用。