Department of Haematology, St Vincent's Public Hospital, Sydney, New South Wales, Australia.
Intern Med J. 2013 Aug;43(8):946-8. doi: 10.1111/imj.12216.
We describe a case of severe hyperglycaemia resulting in diabetic ketoacidosis secondary to L-asparaginase. There are few reports of this potentially life-threatening complication, particularly in the English literature. Awareness and recognition of this preventable and manageable problem will improve safe delivery of this anti-leukaemic drug.
我们描述了一例由 L-天冬酰胺酶引起的严重高血糖导致糖尿病酮症酸中毒的病例。这种潜在的危及生命的并发症在英文文献中鲜有报道。提高对这种可预防和可治疗问题的认识,将有助于安全使用这种抗白血病药物。