Suppr超能文献

婴儿球后阻滞的疗效——与静脉注射芬太尼用于婴儿白内障手术围手术期镇痛的比较。

Efficacy of subtenon block in infants - a comparison with intravenous fentanyl for perioperative analgesia in infantile cataract surgery.

作者信息

Sethi Sameer, Ghai Babita, Sen Indu, Ram Jagat, Wig Jyotsna

机构信息

Department of Anesthesia and Intensive Care, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

Paediatr Anaesth. 2013 Nov;23(11):1015-20. doi: 10.1111/pan.12227. Epub 2013 Aug 6.

Abstract

BACKGROUND

General anesthesia with opioids provides good perioperative analgesia in infantile ocular surgeries but is associated with the risk of respiratory depression and postoperative emesis. This study aimed to assess the effectiveness of subtenon block for providing perioperative analgesia in infants undergoing cataract surgeries.

METHODS

In this prospective, randomized, controlled, double-blinded trial, 63 infants of ASA grade I and II (1-12 months) were recruited to receive either subtenon block (Group SB) or 1 μg·kg(-1) i.v. fentanyl (Group F) after induction of anesthesia. Primary outcome was the number of infants requiring rescue analgesia during 4-h study period before discharge of the infants. Secondary outcomes assessed were CRIES pain score, incidence of oculocardiac reflex, surgical difficulty, and incidence of postoperative emesis.

RESULTS

The number of infants requiring rescue analgesia during 4-h study period was significantly less in Group SB (n = 6/32, 18.8%) compared to Group F (n = 14/31, 45.2%, P = 0.032). CRIES scores were significantly lower at and after 40 min compared to immediate postoperative period in Group F while these were comparable at all time intervals in Group SB. CRIES scores were significantly lower in Group SB compared to Group F at all time intervals except at 1 h. The incidence of oculocardiac reflex and the postoperative emesis were comparable in both the groups.

CONCLUSION

Subtenon block is an effective superior technique for postoperative analgesia compared to intravenous fentanyl in infants undergoing cataract surgery.

摘要

背景

在婴儿眼科手术中,使用阿片类药物的全身麻醉可提供良好的围手术期镇痛效果,但存在呼吸抑制和术后呕吐的风险。本研究旨在评估球后阻滞在接受白内障手术的婴儿中提供围手术期镇痛的有效性。

方法

在这项前瞻性、随机、对照、双盲试验中,招募了63例ASA I级和II级(1 - 12个月)的婴儿,在麻醉诱导后接受球后阻滞(SB组)或静脉注射1μg·kg⁻¹芬太尼(F组)。主要结局是婴儿出院前4小时研究期间需要补救镇痛的婴儿数量。评估的次要结局包括CRIES疼痛评分、眼心反射发生率、手术难度和术后呕吐发生率。

结果

在4小时研究期间,SB组(n = 6/32,18.8%)需要补救镇痛的婴儿数量明显少于F组(n = 14/31,45.2%,P = 0.032)。F组在术后40分钟及之后的CRIES评分明显低于术后即刻,而SB组在所有时间间隔的CRIES评分相当。除1小时外,SB组在所有时间间隔的CRIES评分均明显低于F组。两组的眼心反射发生率和术后呕吐发生率相当。

结论

在接受白内障手术的婴儿中,与静脉注射芬太尼相比,球后阻滞是一种有效的术后镇痛的优越技术。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验