Ugwu E O, Onah H E, Obi S N, Dim C C, Okezie O A, Chigbu C O, Okoro O S
Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
J Obstet Gynaecol. 2013 Aug;33(6):572-7. doi: 10.3109/01443615.2013.786030.
This randomised controlled trial was carried out over a 14-month period in a tertiary health institution in Nigeria, to determine the effectiveness of Foley catheter and synchronous low dose misoprostol for pre-labour cervical ripening. Term pregnant women with unfavourable cervices (Bishop's score < 6) requiring cervical ripening/induction of labour were assigned randomly into three groups: Group A, transcervical Foley catheter was used synchronously with low dose intravaginal misoprostol; Group B, transcervical Foley catheter alone was used and Group C, low dose intravaginal misoprostol alone was used. The time to achieve a favourable cervical status as well as vaginal delivery was significantly shorter in the synchronous group than in the control groups (p < 0.05). The synchronous use of Foley catheter and misoprostol is very effective in cervical ripening and should be considered in clinical situations where there is need to hasten vaginal delivery in the presence of an unripe cervix.
这项随机对照试验在尼日利亚的一家三级医疗机构中进行，为期14个月，以确定Foley导管与同步低剂量米索前列醇用于引产术前宫颈成熟的有效性。需要宫颈成熟/引产的宫颈条件不佳（Bishop评分<6）的足月孕妇被随机分为三组：A组，经宫颈Foley导管与低剂量阴道内米索前列醇同步使用；B组，仅使用经宫颈Foley导管；C组，仅使用低剂量阴道内米索前列醇。同步组达到良好宫颈状态以及阴道分娩的时间明显短于对照组（p<0.05）。Foley导管与米索前列醇同步使用在宫颈成熟方面非常有效，在宫颈未成熟但需要加速阴道分娩的临床情况下应予以考虑。
