Rath W, Kehl S
Faculty of Medicine, Gynaecology and Obstetrics, University Hospital RWTH Aachen, Aachen.
Department of Obstetrics and Gynaecology, University Hospital Erlangen, Erlangen.
Geburtshilfe Frauenheilkd. 2015 Nov;75(11):1130-1139. doi: 10.1055/s-0035-1558094.
Due to rising rates of labour induction in industrialised countries, safe and effective methods of induction have once again become a focus of interest and research. Prostaglandins are effective for cervical ripening and induction of uterine contractions. They do, however, cause overstimulation of the uterus in up to 20 % of cases, sometimes causing changes in fetal heart rate. Transcervical balloon catheters provide an alternative to prostaglandins for labour induction and have been used for this purpose for almost 50 years. This induction method has experienced a recent renaissance in clinical practice that is reflected in an annually rising number of publications on its use. Balloon catheters allow gentle ripening of the cervix without causing uterine overstimulation. The two catheters available are the Foley catheter (off-label use) and the double balloon catheter, which is licensed for use in induction of labour. Both are as effective as prostaglandins, and do not increase the risk of infection to mother or child. Catheter induction also requires less monitoring compared to prostaglandins resulting in improved patient satisfaction. Balloon catheters provide a useful and promising option to achieve vaginal delivery despite failed prostaglandin induction. Intravenous oxytocin is nevertheless required in up to 85 % of cases for adequate induction/augmentation of contractions. Balloon catheters, vaginal PGE and misoprostol are equally effective in the context of an unripe/unfavourable cervix, the rate of uterine hyperstimulation being significantly lower, and the need for oxytocin significantly higher for catheters. Balloon catheters are increasingly being used in combination or sequentially with oral/vaginal misoprostol, although there is currently inadequate published data on the subject. International guidelines recommend the use of balloon catheters for labour induction with an unripe cervix (also following previous caesarean section) as an alternative to prostaglandins, particularly when these are not available or are contraindicated.
由于工业化国家引产率不断上升,安全有效的引产方法再次成为人们关注和研究的焦点。前列腺素对宫颈成熟和诱发子宫收缩有效。然而,在高达20%的病例中,它们会导致子宫过度刺激,有时会引起胎儿心率变化。经宫颈球囊导管为引产提供了一种替代前列腺素的方法,并且已经用于此目的近50年。这种引产方法最近在临床实践中复兴,这体现在关于其使用的出版物数量逐年增加。球囊导管可使宫颈温和成熟,而不会引起子宫过度刺激。现有的两种导管是Foley导管(标签外使用)和双球囊导管,后者被批准用于引产。两者都与前列腺素一样有效,并且不会增加母婴感染风险。与前列腺素相比,导管引产所需的监测也更少,从而提高了患者满意度。尽管前列腺素引产失败,但球囊导管为实现阴道分娩提供了一种有用且有前景的选择。然而,在高达85%的病例中,仍需要静脉注射缩宫素以充分诱发/增强宫缩。在宫颈未成熟/条件不佳的情况下,球囊导管、阴道用前列腺素E和米索前列醇同样有效,子宫过度刺激的发生率显著降低,而导管引产对缩宫素的需求显著更高。球囊导管越来越多地与口服/阴道米索前列醇联合使用或序贯使用,尽管目前关于这一主题的已发表数据不足。国际指南建议,对于宫颈未成熟的引产(既往剖宫产术后也是如此),使用球囊导管作为前列腺素的替代方法,特别是当前列腺素不可用或有禁忌证时。