Fernandez-Lozano Carlos, Lopez-Campos Guillermo, Seoane Jose A, Lopez-Alonso Victoria, Dorado Julian, Martín-Sanchez Fernando, Pazos Alejandro
Information and Communications Technologies Department, University of A Coruña, Spain.
Stud Health Technol Inform. 2013;192:979.
The development of personalized medicine is tightly linked with the correct exploitation of molecular data, especially those associated with the genome sequence along with these use of genomic data there is an increasing demand to share these data for research purposes. Transition of clinical data to research is based in the anonymization of these data so the patient cannot be identified, the use of genomic data poses a great challenge because its nature of identifying data. In this work we have analyzed current methods for genome anonymization and propose a one way encryption method that may enable the process of genomic data sharing accessing only to certain regions of genomes for research purposes.
个性化医疗的发展与分子数据的正确利用紧密相连，尤其是那些与基因组序列相关的数据。随着基因组数据的使用，出于研究目的共享这些数据的需求日益增加。临床数据向研究的转化基于对这些数据的匿名化处理，这样就无法识别患者，而基因组数据的使用带来了巨大挑战，因为其具有识别数据的特性。在这项工作中，我们分析了当前的基因组匿名化方法，并提出了一种单向加密方法，该方法可能使基因组数据共享过程仅为研究目的而访问基因组的某些区域成为可能。
