Boylan K B, Chin J H, DeArmond S J
Department of Neurology, School of Medicine, University of California, San Francisco 94143.
Neurology. 1990 Sep;40(9):1458-61. doi: 10.1212/wnl.40.9.1458.
We report a case of a 55-year-old man in whom progressive extrapyramidal disease developed nearly 1 year after resuscitation from cardiopulmonary arrest. Parkinsonian features evolved within 3 months, and progressive generalized dystonia developed after 11 months. CT and MRI revealed bilateral basal ganglia infarction. Autopsy after 4 years of illness showed bilateral basal ganglia necrosis with preserved corticospinal tracts. These findings support earlier suggestions that postinfarction dystonia is mediated by a pyramidal system lacking normal striatal control.