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入院时的处方错误及其潜在影响:一项混合方法研究。

Prescribing errors on admission to hospital and their potential impact: a mixed-methods study.

机构信息

Pharmacy Department, Royal Liverpool University Hospital, , Liverpool, UK.

出版信息

BMJ Qual Saf. 2014 Jan;23(1):17-25. doi: 10.1136/bmjqs-2013-001978. Epub 2013 Aug 6.

Abstract

BACKGROUND

Medication errors are an important cause of morbidity and mortality and adversely affect clinical outcomes. Prescribing errors constitute one type of medication error and occur particularly on admission to hospital; little is known about how they arise.

AIM

This study investigated how doctors obtain the information necessary to prescribe on admission to hospital, and the number and potential impact of any errors.

SETTING

English teaching hospital-acute medical unit.

METHODS

Ethics approval was granted. Data were collected over four 1-week periods; November 2009, January 2010, April 2010 and April 2011. The patient admission process was directly observed, field notes were recorded using a standard form. Doctors participated in a structured interview; case notes of all patients admitted during study periods were reviewed.

RESULTS

There were differences between perceived practice stated in interviews and actual practice observed. All 19 doctors interviewed indicated that they would sometimes or always use more than one source of information for a medication history; a single source was used in 31/68 observed cases. 7/12 doctors both observed and interviewed indicated that they would confirm medication with patients; observations showed they did so for only 2/12 patients. In 66/68 cases, the patient/carer was able to discuss medication, 14 were asked no medication-related questions. Of 688 medication charts reviewed, 318 (46.2%) had errors. A total of 851 errors were identified; 737/851 (86.6%) involved omission of a medicine; 94/737 (12.8%) of these were potentially significant.

CONCLUSIONS

Although doctors know the importance of obtaining an accurate medication history and checking prescriptions with patients, they often fail to put this into practice, resulting in prescribing errors.

摘要

背景

用药错误是发病率和死亡率的一个重要原因,并且对临床结果有不利影响。处方错误是用药错误的一种类型,尤其在入院时发生;关于其产生的原因知之甚少。

目的

本研究调查了医生在入院时获取处方所需信息的方式,以及任何错误的数量和潜在影响。

设置

英国教学医院-急性内科病房。

方法

获得伦理批准。数据在四个为期一周的时间段内收集;2009 年 11 月、2010 年 1 月、2010 年 4 月和 2011 年 4 月。直接观察病人入院过程,使用标准表格记录现场记录。医生参与了结构化访谈;回顾了研究期间所有入院患者的病历。

结果

访谈中陈述的感知实践与实际观察到的实践之间存在差异。接受访谈的 19 名医生均表示,他们有时或总是会使用多种信息来源来获取药物史;在观察到的 68 例病例中,仅使用了单一来源。12 名接受访谈和观察的医生中有 7 名表示会与患者确认药物;观察结果显示,他们仅对 12 名患者中的 2 名进行了确认。在 68 例病例中,患者/照顾者能够讨论药物,14 例未询问与药物相关的问题。在审查的 688 份药物图表中,有 318 份(46.2%)存在错误。共发现 851 个错误;737/851(86.6%)涉及遗漏一种药物;737 个中有 94 个(12.8%)可能是严重的错误。

结论

尽管医生知道获取准确的药物史并与患者核对处方的重要性,但他们往往未能付诸实践,导致处方错误。

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