Cukic Vesna, Lovre Vladimir
Clinic for Pulmonary Diseases and TB "Podhrastovi", Clinical center of University of Sarajevo, Bosnia and Herzegovina.
Mater Sociomed. 2012;24(3):165-70. doi: 10.5455/msm.2012.24.165-170.
In recent years there has been increase in the number of patients who need thoracic surgery - first of all different types of pulmonary resection because of primary bronchial cancer, and very often among patients whose lung function is impaired due to different degree of bronchial obstruction so it is necessary to assess functional status before and after lung surgery to avoid the development of respiratory insufficiency.
To show the changes in the level of arterial blood gases after various ranges of lung resection.
The study was done on 71 patients surgically treated at the Clinic for Thoracic Surgery KCU Sarajevo, who were previously treated at the Clinic for Pulmonary Diseases "Podhrastovi" in the period from 01. 06. 2009. to 01. 09. 2011. Different types of lung resection were made. Patients whose percentage of ppoFEV1 was (prognosed postoperative FEV1) was less than 30% of normal values of FEV1 for that patients were not given a permission for lung resection. We monitored the changes in levels-partial pressures of blood gases (PaO2, PaCO2 and SaO2) one and two months after resection and compared them to preoperative values. As there were no significant differences between the values obtained one and two months after surgery, in the results we showed arterial blood gas analysis obtained two months after surgical resection. Results were statistically analyzed by SPSS and Microsoft Office Excel. Statistical significance was determined at an interval of 95%.
In 59 patients (83%) there was an increase, and in 12 patients (17%) there was a decrease of PaO2, compared to preoperative values. In 58 patients (82%) there was a decrease, and in 13 patients (18%) there was an increase in PaCO2, compared to preoperative values. For all subjects (group as whole): The value of the PaO2 was significantly increased after lung surgery compared to preoperative values (p <0.05) so is the value of the SaO2%. The value of the PaCO2 was significantly decreased after lung surgery compared to preoperative values (p <0.05). Respiratory insufficiency was developed in none of patients.
If the % ppoFEV1 (% prognosed postoperative FEV1) is bigger than 30% of normal values of FEV1 (according to sex, weight, height, age) in patient planned for lung resection surgery there is no development of respiratory insufficiency after resection.
近年来,需要进行胸外科手术的患者数量有所增加——首先是因原发性支气管癌而进行的各种类型的肺切除术,而且在因不同程度的支气管阻塞导致肺功能受损的患者中这种情况非常常见,因此有必要在肺手术前后评估功能状态,以避免呼吸功能不全的发生。
展示不同范围肺切除术后动脉血气水平的变化。
该研究对在萨拉热窝KCU胸外科诊所接受手术治疗的71例患者进行,这些患者此前于2009年6月1日至2011年9月1日期间在“Podhrastovi”肺病诊所接受治疗。进行了不同类型的肺切除术。预计术后第一秒用力呼气量(ppoFEV1)百分比低于该患者FEV1正常数值30%的患者未被允许进行肺切除。我们监测了切除术后1个月和2个月时血气水平(动脉血氧分压、动脉血二氧化碳分压和动脉血氧饱和度)的变化,并将其与术前值进行比较。由于术后1个月和2个月获得的值之间没有显著差异,因此我们在结果中展示了手术切除术后2个月获得的动脉血气分析结果。结果采用SPSS和Microsoft Office Excel进行统计学分析。统计学显著性在95%的区间内确定。
与术前值相比,59例患者(83%)的动脉血氧分压升高,12例患者(17%)降低。与术前值相比,58例患者(82%)的动脉血二氧化碳分压降低,13例患者(18%)升高。对于所有受试者(作为整体的组):肺手术后动脉血氧分压值与术前值相比显著升高(p<0.05),动脉血氧饱和度值也是如此。肺手术后动脉血二氧化碳分压值与术前值相比显著降低(p<0.05)。无一例患者发生呼吸功能不全。
对于计划进行肺切除手术的患者,如果预计术后第一秒用力呼气量百分比(ppoFEV1)大于FEV1正常数值(根据性别、体重、身高、年龄)的30%,则切除术后不会发生呼吸功能不全。