Cukic Vesna
Clinic for Pulmonary Diseases and TB "Podhrastovi", Clinical Centre of Sarajevo University, Bosnia and Herzegovina.
Med Arch. 2014 Aug;68(4):231-5. doi: 10.5455/medarh.2014.68.231-235. Epub 2014 Jul 31.
In recent years an increasing number of lung resections are being done because of the rising prevalence of lung cancer that occurs mainly in patients with limited lung function, what is caused with common etiologic factor - smoking cigarettes.
To determine how big the loss of lung function is after surgical resection of lung of different range.
The study was done on 58 patients operated at the Clinic for thoracic surgery KCU Sarajevo, previously treated at the Clinic for pulmonary diseases "Podhrastovi" in the period from 01.06.2012. to 01.06.2014. The following resections were done: pulmectomy (left, right), lobectomy (upper, lower: left and right). The values of postoperative pulmonary function were compared with preoperative ones. As a parameter of lung function we used FEV1 (forced expiratory volume in one second), and changes in FEV1 are expressed in liters and in percentage of the recorded preoperative and normal values of FEV1. Measurements of lung function were performed seven days before and 2 months after surgery.
Postoperative FEV1 was decreased compared to preoperative values. After pulmectomy the maximum reduction of FEV1 was 44%, and after lobectomy it was 22% of the preoperative values.
Patients with airway obstruction are limited in their daily life before the surgery, and an additional loss of lung tissue after resection contributes to their inability. Potential benefits of lung resection surgery should be balanced in relation to postoperative morbidity and mortality.
近年来,由于肺癌患病率上升,越来越多的肺切除术得以开展,而肺癌主要发生在肺功能有限的患者中,这是由常见病因——吸烟导致的。
确定不同范围的肺切除术后肺功能损失程度。
该研究对58例在萨拉热窝KCU胸外科诊所接受手术的患者进行,这些患者于2012年6月1日至2014年6月1日期间曾在“Podhrastovi”肺病诊所接受治疗。进行了以下切除术:全肺切除术(左、右)、肺叶切除术(上、下:左、右)。将术后肺功能值与术前值进行比较。作为肺功能参数,我们使用第一秒用力呼气容积(FEV1),FEV1的变化以升为单位表示,并以术前记录值和FEV1正常值的百分比表示。在手术前7天和术后2个月进行肺功能测量。
术后FEV1较术前值降低。全肺切除术后FEV1的最大降幅为44%,肺叶切除术后为术前值的22%。
气道阻塞患者在手术前日常生活就受到限制,切除术后肺组织的额外损失加剧了他们的功能障碍。肺切除手术的潜在益处应与术后发病率和死亡率相权衡。