体外生命支持治疗急性呼吸窘迫综合征。

Section of Pulmonary Medicine, Nationwide Children's Hospital, The Ohio State University Wexner Medical Center, Columbus, OH, USA ; Section of Heart Center, Nationwide Children's Hospital, Columbus, OH, USA ; Department of Pediatrics, The Ohio State University Wexner Medical Center, Columbus, OH, USA ; Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

Ann Thorac Med. 2013 Jul;8(3):133-41. doi: 10.4103/1817-1737.114290.

The morbidity and mortality of acute respiratory distress syndrome remain to be high. Over the last 50 years, the clinical management of these patients has undergone vast changes. Significant improvement in the care of these patients involves the development of mechanical ventilation strategies, but the benefits of these strategies remain controversial. With a growing trend of extracorporeal support for critically ill patients, we provide a historical review of extracorporeal membrane oxygenation (ECMO) including its failures and successes as well as discussing extracorporeal devices now available or nearly accessible while examining current clinical indications and trends of ECMO in respiratory failure.

急性呼吸窘迫综合征的发病率和死亡率仍然很高。在过去的 50 年中，这些患者的临床管理发生了巨大变化。这些患者护理的显著改善涉及机械通气策略的发展，但这些策略的益处仍存在争议。随着体外生命支持在危重病患者中的应用趋势不断增长，我们提供了体外膜氧合（ECMO）的历史回顾，包括其失败和成功，以及讨论目前可获得或即将获得的体外设备，同时检查 ECMO 在呼吸衰竭中的当前临床适应症和趋势。